The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy
Immunotherapy of malignant tumor is a verified and crucial anti-tumor strategy to help patients with cancer for prolonging prognostic survival. It is a novel anticancer tactics that activates the immune system to discern and damage cancer cells, thereby prevent them from proliferating. However, immu...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-06-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2021.687399/full |
| _version_ | 1818646999520509952 |
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| author | Jia-shuai He Shi-jin Liu Yi-ran Zhang Xiao-dong Chu Zheng-bin Lin Zhan Zhao Sheng-hui Qiu Yan-guan Guo Hui Ding Yun-long Pan Jing-hua Pan |
| author_facet | Jia-shuai He Shi-jin Liu Yi-ran Zhang Xiao-dong Chu Zheng-bin Lin Zhan Zhao Sheng-hui Qiu Yan-guan Guo Hui Ding Yun-long Pan Jing-hua Pan |
| author_sort | Jia-shuai He |
| collection | DOAJ |
| description | Immunotherapy of malignant tumor is a verified and crucial anti-tumor strategy to help patients with cancer for prolonging prognostic survival. It is a novel anticancer tactics that activates the immune system to discern and damage cancer cells, thereby prevent them from proliferating. However, immunotherapy still faces many challenges in view of clinical efficacy and safety issues. Various nanomaterials, especially gold nanoparticles (AuNPs), have been developed not only for anticancer treatment but also for delivering antitumor drugs or combining other treatment strategies. Recently, some studies have focused on AuNPs for enhancing cancer immunotherapy. In this review, we summarized how AuNPs applicated as immune agents, drug carriers or combinations with other immunotherapies for anticancer treatment. AuNPs can not only act as immune regulators but also deliver immune drugs for cancer. Therefore, AuNPs are candidates for enhancing the efficiency and safety of cancer immunotherapy. |
| first_indexed | 2024-12-17T00:55:34Z |
| format | Article |
| id | doaj.art-1167fde94086445ab39296987d6c8dce |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-17T00:55:34Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-1167fde94086445ab39296987d6c8dce2022-12-21T22:09:37ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122021-06-011210.3389/fphar.2021.687399687399The Application of and Strategy for Gold Nanoparticles in Cancer ImmunotherapyJia-shuai HeShi-jin LiuYi-ran ZhangXiao-dong ChuZheng-bin LinZhan ZhaoSheng-hui QiuYan-guan GuoHui DingYun-long PanJing-hua PanImmunotherapy of malignant tumor is a verified and crucial anti-tumor strategy to help patients with cancer for prolonging prognostic survival. It is a novel anticancer tactics that activates the immune system to discern and damage cancer cells, thereby prevent them from proliferating. However, immunotherapy still faces many challenges in view of clinical efficacy and safety issues. Various nanomaterials, especially gold nanoparticles (AuNPs), have been developed not only for anticancer treatment but also for delivering antitumor drugs or combining other treatment strategies. Recently, some studies have focused on AuNPs for enhancing cancer immunotherapy. In this review, we summarized how AuNPs applicated as immune agents, drug carriers or combinations with other immunotherapies for anticancer treatment. AuNPs can not only act as immune regulators but also deliver immune drugs for cancer. Therefore, AuNPs are candidates for enhancing the efficiency and safety of cancer immunotherapy.https://www.frontiersin.org/articles/10.3389/fphar.2021.687399/fullnanomaterialsgold nanoparticlescancer immunotherapynanocarriersdrug delivery system |
| spellingShingle | Jia-shuai He Shi-jin Liu Yi-ran Zhang Xiao-dong Chu Zheng-bin Lin Zhan Zhao Sheng-hui Qiu Yan-guan Guo Hui Ding Yun-long Pan Jing-hua Pan The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy Frontiers in Pharmacology nanomaterials gold nanoparticles cancer immunotherapy nanocarriers drug delivery system |
| title | The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy |
| title_full | The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy |
| title_fullStr | The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy |
| title_full_unstemmed | The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy |
| title_short | The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy |
| title_sort | application of and strategy for gold nanoparticles in cancer immunotherapy |
| topic | nanomaterials gold nanoparticles cancer immunotherapy nanocarriers drug delivery system |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2021.687399/full |
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