Common Dysregulation of Innate Immunity Pathways in Human Primary Astrocytes Infected With Chikungunya, Mayaro, Oropouche, and Zika Viruses

Common Dysregulation of Innate Immunity Pathways in Human Primary Astrocytes Infected With Chikungunya, Mayaro, Oropouche, and Zika Viruses

Arboviruses pose a major threat throughout the world and represent a great burden in tropical countries of South America. Although generally associated with moderate febrile illness, in more severe cases they can lead to neurological outcomes, such as encephalitis, Guillain-Barré syndrome, and Conge...

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Main Authors: Victor Emmanuel Viana Geddes, Otávio José Bernardes Brustolini, Liliane Tavares de Faria Cavalcante, Filipe Romero Rebello Moreira, Fernando Luz de Castro, Ana Paula de Campos Guimarães, Alexandra Lehmkuhl Gerber, Camila Menezes Figueiredo, Luan Pereira Diniz, Eurico de Arruda Neto, Amilcar Tanuri, Renan Pedra Souza, Iranaia Assunção-Miranda, Soniza Vieira Alves-Leon, Luciana Ferreira Romão, Jorge Paes Barreto Marcondes de Souza, Ana Tereza Ribeiro de Vasconcelos, Renato Santana de Aguiar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chikungunya
Mayaro
Oropouche
Zika
innate immunity
astrocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.641261/full

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