2464 Sexual dimorphism in a mouse model of syndromic thoracic aortic aneurysm

OBJECTIVES/SPECIFIC AIMS: Pre-clinical and clinical observations have noted that increased aortic dilation is associated with male sex. Using an experimental model of severe, syndromic thoracic aortic aneurysms, we quantify aortic dilation and elastin stability in male Versus female mice. METHODS/ST...

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Bibliographic Details
Main Authors: Zheying Chen, Alan Daugherty, Mary Sheppard
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866118001218/type/journal_article