Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction

Aim. To examine the changes in left ventricular (LV) local contractility (LC) and systolic function at rest and during cold stress test in patients with acute myocardial infarction (AMI).Material and methods. The study included 67 AMI patients (mean age 56,41±1,06 years). The standard echocardiograp...

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Main Authors: V. R. Veber, M. P. Rubanova, K. A. Antonov, S. V. Zhamylova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2008-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1059
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author V. R. Veber
M. P. Rubanova
K. A. Antonov
S. V. Zhamylova
author_facet V. R. Veber
M. P. Rubanova
K. A. Antonov
S. V. Zhamylova
author_sort V. R. Veber
collection DOAJ
description Aim. To examine the changes in left ventricular (LV) local contractility (LC) and systolic function at rest and during cold stress test in patients with acute myocardial infarction (AMI).Material and methods. The study included 67 AMI patients (mean age 56,41±1,06 years). The standard echocardiography examination took place at Day 10 after acute coronary syndrome (ACS) development. LC analysis was based on dividing LV into 16 segments.Results. With similar baseline LC and global contractility (GC), cold stress test identified various reactions in AMI patients, which might reflect various mechanisms for each reaction type. In groups 1 and 2, cold stress test causeddifferent two6phase reactions. At the same time, in Group 1, negative inotropic response and decreased LC were observed; in Group 2, both LC and GC inotropic effects were positive. Group 3 was characterized by unchanged LV LC. Younger AMI patients (40-49 years) typically demonstrated reaction 1, with reduced LC and "early" angina clinics. In older ages, reaction 2, with improved LC and increased LV volume at rest, was more typical. Cold stress test reaction, described by decreased LV LC, is associated with poor prognosis, due to high frequency of recurrent ACS (33,3%). Conclusion. Cold stress test could be used for prognosis assessment in AMI patients.
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spelling doaj.art-116f595a92f84740967c7190c645b8e52024-10-17T12:21:26Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-02-01714651772Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarctionV. R. Veber0M. P. Rubanova1K. A. Antonov2S. V. Zhamylova3Yaroslav the Wise Novgorod State University - Novgorod Branch, State Research Center for Preventive Medicine. Veliky NovgorodYaroslav the Wise Novgorod State University - Novgorod Branch, State Research Center for Preventive Medicine. Veliky NovgorodYaroslav the Wise Novgorod State University - Novgorod Branch, State Research Center for Preventive Medicine. Veliky NovgorodYaroslav the Wise Novgorod State University - Novgorod Branch, State Research Center for Preventive Medicine. Veliky NovgorodAim. To examine the changes in left ventricular (LV) local contractility (LC) and systolic function at rest and during cold stress test in patients with acute myocardial infarction (AMI).Material and methods. The study included 67 AMI patients (mean age 56,41±1,06 years). The standard echocardiography examination took place at Day 10 after acute coronary syndrome (ACS) development. LC analysis was based on dividing LV into 16 segments.Results. With similar baseline LC and global contractility (GC), cold stress test identified various reactions in AMI patients, which might reflect various mechanisms for each reaction type. In groups 1 and 2, cold stress test causeddifferent two6phase reactions. At the same time, in Group 1, negative inotropic response and decreased LC were observed; in Group 2, both LC and GC inotropic effects were positive. Group 3 was characterized by unchanged LV LC. Younger AMI patients (40-49 years) typically demonstrated reaction 1, with reduced LC and "early" angina clinics. In older ages, reaction 2, with improved LC and increased LV volume at rest, was more typical. Cold stress test reaction, described by decreased LV LC, is associated with poor prognosis, due to high frequency of recurrent ACS (33,3%). Conclusion. Cold stress test could be used for prognosis assessment in AMI patients.https://cardiovascular.elpub.ru/jour/article/view/1059acute myocardial infarctionlocal contractilityglobal myocardial contractilitystress echocardiography
spellingShingle V. R. Veber
M. P. Rubanova
K. A. Antonov
S. V. Zhamylova
Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
Кардиоваскулярная терапия и профилактика
acute myocardial infarction
local contractility
global myocardial contractility
stress echocardiography
title Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
title_full Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
title_fullStr Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
title_full_unstemmed Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
title_short Local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
title_sort local contractility and systolic function of left ventricular myocardium at rest and during cold stress test in patients with acute myocardial infarction
topic acute myocardial infarction
local contractility
global myocardial contractility
stress echocardiography
url https://cardiovascular.elpub.ru/jour/article/view/1059
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AT kaantonov localcontractilityandsystolicfunctionofleftventricularmyocardiumatrestandduringcoldstresstestinpatientswithacutemyocardialinfarction
AT svzhamylova localcontractilityandsystolicfunctionofleftventricularmyocardiumatrestandduringcoldstresstestinpatientswithacutemyocardialinfarction