Case report: A relatively rare adverse event caused by carbetocin— placenta interception

Placenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of pla...

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Main Authors: Jun-Qiang Li, Yong-Chi Zhan, Xiao-Dong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1112694/full
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author Jun-Qiang Li
Jun-Qiang Li
Yong-Chi Zhan
Xiao-Dong Wang
author_facet Jun-Qiang Li
Jun-Qiang Li
Yong-Chi Zhan
Xiao-Dong Wang
author_sort Jun-Qiang Li
collection DOAJ
description Placenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of placental separation in the third stage of labor. A protuberance with gross subserous blood vessels in the left fundus of the uterus was detected and was misdiagnosed as placental accreta. The patient was transferred to the district referral hospital to manage the protuberance after stitching up the incision. On opening the original incision in the tertiary hospital, the protuberance disappeared, and the placenta was found in the lower segment of the uterus cavity. The intercepted placenta showed a spontaneous resolution from the uterine wall and was removed intact. This case report details the typical presentation of placenta interception to make obstetricians aware of the possibility that carbetocin might lead to this adverse event.
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spelling doaj.art-1170cc09cd7a4651b589f17eff3b16a92024-11-11T11:19:41ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-03-011410.3389/fphar.2023.11126941112694Case report: A relatively rare adverse event caused by carbetocin— placenta interceptionJun-Qiang Li0Jun-Qiang Li1Yong-Chi Zhan2Xiao-Dong Wang3Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, ChinaDepartment of Obstetrics and Gynecology, The Third People’s Hospital of Chengdu, Chengdu, ChinaDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, ChinaDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, ChinaPlacenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of placental separation in the third stage of labor. A protuberance with gross subserous blood vessels in the left fundus of the uterus was detected and was misdiagnosed as placental accreta. The patient was transferred to the district referral hospital to manage the protuberance after stitching up the incision. On opening the original incision in the tertiary hospital, the protuberance disappeared, and the placenta was found in the lower segment of the uterus cavity. The intercepted placenta showed a spontaneous resolution from the uterine wall and was removed intact. This case report details the typical presentation of placenta interception to make obstetricians aware of the possibility that carbetocin might lead to this adverse event.https://www.frontiersin.org/articles/10.3389/fphar.2023.1112694/fullplacenta interceptioncarbetocincesarean sectionexcessive uterine contractioncase report
spellingShingle Jun-Qiang Li
Jun-Qiang Li
Yong-Chi Zhan
Xiao-Dong Wang
Case report: A relatively rare adverse event caused by carbetocin— placenta interception
Frontiers in Pharmacology
placenta interception
carbetocin
cesarean section
excessive uterine contraction
case report
title Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_full Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_fullStr Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_full_unstemmed Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_short Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_sort case report a relatively rare adverse event caused by carbetocin placenta interception
topic placenta interception
carbetocin
cesarean section
excessive uterine contraction
case report
url https://www.frontiersin.org/articles/10.3389/fphar.2023.1112694/full
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AT xiaodongwang casereportarelativelyrareadverseeventcausedbycarbetocinplacentainterception