Regulation of Herpes Simplex Virus gB-Induced Cell-Cell Fusion by Mutant Forms of gH/gL in the Absence of gD and Cellular Receptors

ABSTRACT Herpesvirus entry requires the viral glycoprotein triad of gB and gH/gL to carry out fusion between the virion envelope and a cellular membrane in order to release the nucleocapsid into the target cell. Herpes simplex virus (HSV) also requires glycoprotein gD to initiate the fusion cascade...

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Bibliographic Details
Main Authors: Doina Atanasiu, Tina M. Cairns, J. Charles Whitbeck, Wan Ting Saw, Samhita Rao, Roselyn J. Eisenberg, Gary H. Cohen
Format: Article
Language:English
Published: American Society for Microbiology 2013-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00046-13