Treatment of ARVI and influenza in patients with arterial hypertension
Aim: to study the flow phenomena of influenza and ARVI in patients with arterial hypertension, as well as the effectiveness of antiviral therapy. Materials and methods. Analyzed data was collected during the international multicenter prospective observational FLU-EE study "Treatment of ARVI and...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2019-09-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/33617/pdf |
| _version_ | 1828376782894530560 |
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| author | E V Silina I G Sitnikov V C Fazylov G A Yeganyan |
| author_facet | E V Silina I G Sitnikov V C Fazylov G A Yeganyan |
| author_sort | E V Silina |
| collection | DOAJ |
| description | Aim: to study the flow phenomena of influenza and ARVI in patients with arterial hypertension, as well as the effectiveness of antiviral therapy. Materials and methods. Analyzed data was collected during the international multicenter prospective observational FLU-EE study "Treatment of ARVI and influenza in routine clinical practice". The study included 18946 patients with established diagnosis of influenza or ARVI of varying severity. 577 patients 51-70 years old who have a history of arterial hypertension (70% of women) were selected from this cohort. These patients regularly received angiotensin - converting enzyme inhibitors for treatment in monotherapy or in combination with other drugs, used to heal diseases of the cardiovascular system. Patients were divided into two groups depending on the therapy. The first group received symptomatic treatment of influenza and ARVI (comparison group, n=86); the second group received the antiviral drug Kagocel in the complex treatment (n=491). Results. Persons with arterial hypertension and other diseases of the cardiovascular system are at risk for severe flu. The administration of the antiviral drug Kagocel as part of the complex therapy of influenza and ARVI makes it possible to speed up the regression of the intoxication syndrome, reduce the incidence of bacterial complications by 36% and the need for antibiotic therapy by 38%. Moreover, a positive effect was registered both with the early treatment of patients for medical help (by 45%) and with delayed treatment, on the 3rd day and later (by 35%). Conclusion. The use of the antiviral drug Kagocel as part of complex therapy for influenza and other acute respiratory viral infections has shown its effectiveness for different groups of patients, including hypertension, despite the fact that cardiovascular pathology, often combined with comorbid diseases, significantly worsens the course and outcome of ARVI. |
| first_indexed | 2024-04-14T08:04:54Z |
| format | Article |
| id | doaj.art-11749041b2d041829eb3ec59b9d37755 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-04-14T08:04:54Z |
| publishDate | 2019-09-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-11749041b2d041829eb3ec59b9d377552022-12-22T02:04:47Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422019-09-01919536110.26442/00403660.2019.09.00033230346Treatment of ARVI and influenza in patients with arterial hypertensionE V Silina0I G Sitnikov1V C Fazylov2G A Yeganyan3Sechenov First Moscow State Medical University (Sechenov University)Yaroslavl State Medical UniversityKazan State Medical UniversityHeratsi Yerevan State Medical UniversityAim: to study the flow phenomena of influenza and ARVI in patients with arterial hypertension, as well as the effectiveness of antiviral therapy. Materials and methods. Analyzed data was collected during the international multicenter prospective observational FLU-EE study "Treatment of ARVI and influenza in routine clinical practice". The study included 18946 patients with established diagnosis of influenza or ARVI of varying severity. 577 patients 51-70 years old who have a history of arterial hypertension (70% of women) were selected from this cohort. These patients regularly received angiotensin - converting enzyme inhibitors for treatment in monotherapy or in combination with other drugs, used to heal diseases of the cardiovascular system. Patients were divided into two groups depending on the therapy. The first group received symptomatic treatment of influenza and ARVI (comparison group, n=86); the second group received the antiviral drug Kagocel in the complex treatment (n=491). Results. Persons with arterial hypertension and other diseases of the cardiovascular system are at risk for severe flu. The administration of the antiviral drug Kagocel as part of the complex therapy of influenza and ARVI makes it possible to speed up the regression of the intoxication syndrome, reduce the incidence of bacterial complications by 36% and the need for antibiotic therapy by 38%. Moreover, a positive effect was registered both with the early treatment of patients for medical help (by 45%) and with delayed treatment, on the 3rd day and later (by 35%). Conclusion. The use of the antiviral drug Kagocel as part of complex therapy for influenza and other acute respiratory viral infections has shown its effectiveness for different groups of patients, including hypertension, despite the fact that cardiovascular pathology, often combined with comorbid diseases, significantly worsens the course and outcome of ARVI.https://ter-arkhiv.ru/0040-3660/article/viewFile/33617/pdfinfluenzaacute respiratory viral infectionarterial hypertensionpathology of the cardiovascular systemantiviral therapykagocel |
| spellingShingle | E V Silina I G Sitnikov V C Fazylov G A Yeganyan Treatment of ARVI and influenza in patients with arterial hypertension Терапевтический архив influenza acute respiratory viral infection arterial hypertension pathology of the cardiovascular system antiviral therapy kagocel |
| title | Treatment of ARVI and influenza in patients with arterial hypertension |
| title_full | Treatment of ARVI and influenza in patients with arterial hypertension |
| title_fullStr | Treatment of ARVI and influenza in patients with arterial hypertension |
| title_full_unstemmed | Treatment of ARVI and influenza in patients with arterial hypertension |
| title_short | Treatment of ARVI and influenza in patients with arterial hypertension |
| title_sort | treatment of arvi and influenza in patients with arterial hypertension |
| topic | influenza acute respiratory viral infection arterial hypertension pathology of the cardiovascular system antiviral therapy kagocel |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/33617/pdf |
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