Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomasResearch in context

Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomasResearch in context

Background: Olaratumab (LY3012207/IMC-3G3/Lartruvo™) is a fully human monoclonal antibody specific for platelet-derived growth factor receptor alpha (PDGFRα). Phase Ib/II trial results of olaratumab plus doxorubicin in adult patients with advanced soft tissue sarcoma (STS) supported accelerated FDA...

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Bibliographic Details
Main Authors:	Erin J. Song, Kathleen A. Ashcraft, Caitlin D. Lowery, Yvonne M. Mowery, Lixia Luo, Yan Ma, Lorraine Da Silva Campos, Diana M. Cardona, Louis Stancato, David G. Kirsch
Format:	Article
Language:	English
Published:	Elsevier 2019-02-01
Series:	EBioMedicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396419300532

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