Intrinsic resistance of HIV-2 and SIV to the maturation inhibitor GSK2838232

Intrinsic resistance of HIV-2 and SIV to the maturation inhibitor GSK2838232

Show other versions (1)

GSK2838232 (GSK232) is a novel maturation inhibitor that blocks the proteolytic cleavage of HIV-1 Gag at the junction of capsid and spacer peptide 1 (CA/SP1), rendering newly-formed virions non-infectious. To our knowledge, GSK232 has not been tested against HIV-2, and there are limited data regardi...

Full description

Bibliographic Details
Main Authors: Robert A. Smith, Dana N. Raugi, Robert S. Nixon, Jennifer Song, Moussa Seydi, Geoffrey S. Gottlieb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847912/?tool=EBI

Similar Items

Similar Items