Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

A meta-analysis of genome-wide association studies of circulating total-tau levels identifies loci specific to European or African American ancestries, providing further insight to the genetic etiology of neurological diseases.

Bibliographic Details
Main Authors:	Chloé Sarnowski, Mohsen Ghanbari, Joshua C. Bis, Mark Logue, Myriam Fornage, Aniket Mishra, Shahzad Ahmad, Alexa S. Beiser, Eric Boerwinkle, Vincent Bouteloup, Vincent Chouraki, L Adrienne Cupples, Vincent Damotte, Charles S. DeCarli, Anita L. DeStefano, Luc Djoussé, Alison E. Fohner, Carol E. Franz, Tiffany F. Kautz, Jean-Charles Lambert, Michael J. Lyons, Thomas H. Mosley, Kenneth J. Mukamal, Matthew P. Pase, Eliana C. Portilla Fernandez, Robert A. Rissman, Claudia L. Satizabal, Ramachandran S. Vasan, Amber Yaqub, Stephanie Debette, Carole Dufouil, Lenore J. Launer, William S. Kremen, William T. Longstreth, M Arfan Ikram, Sudha Seshadri
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-04-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-022-03287-y

Description
Summary:	A meta-analysis of genome-wide association studies of circulating total-tau levels identifies loci specific to European or African American ancestries, providing further insight to the genetic etiology of neurological diseases.
ISSN:	2399-3642