Glioblastoma cells express crucial enzymes involved in androgen synthesis: 3β‐hydroxysteroid dehydrogenase, 17‐20α‐hydroxylase, 17β‐hydroxysteroid dehydrogenase and 5α‐reductase

Glioblastoma cells express crucial enzymes involved in androgen synthesis: 3β‐hydroxysteroid dehydrogenase, 17‐20α‐hydroxylase, 17β‐hydroxysteroid dehydrogenase and 5α‐reductase

Abstract Glioblastoma (GB) is the most common and aggressive primary brain tumour in adult humans. Therapeutic resistance and tumour recurrence after surgical removal contribute to poor prognosis for glioblastoma patients. Men are known to be more likely than women to develop an aggressive form of G...

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Bibliografski detalji
Glavni autori: Jose Antonio Mondragón Dr, Yesenia Serrano Lic, Andrea Torres, Martin Orozco, Jose Segovia Dr, Gabriel Manjarrez Dr, Marta Catalina Romano
Format: Članak
Jezik:English
Izdano: Wiley 2021-10-01
Serija:Endocrinology, Diabetes & Metabolism
Teme:
cancer
glioblastoma
neurosteroids
steroidogenic enzymes
Online pristup:https://doi.org/10.1002/edm2.289

Internet

https://doi.org/10.1002/edm2.289

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