Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment

Splice-Site Variants in the Gene Encoding GABA-A Receptor Delta Subunit Are Associated with Amphetamine Use in Patients under Methadone Maintenance Treatment

Chronic opioid use disorder patients often also use other substances such as amphetamines. The gene-based analysis method was applied in the genomic database obtained from our previous study with 343 methadone maintenance treatment (MMT) patients. We found that the gene encoding gamma-aminobutyric a...

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Bibliographic Details
Main Authors: Yen-Feng Lin, Wen-Hai Chou, Tung-Hsia Liu, Chiu-Ping Fang, Hsiang-Wei Kuo, Po-Hsiu Kuo, Shih-Jen Tsai, Sheng-Chang Wang, Ren-Hua Chung, Hsiao-Hui Tsou, Andrew C. H. Chen, Yu-Li Liu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
amphetamine use
<i>GABRD</i>
methadone maintenance treatment
psychostimulant
polysubstance abuse
Online Access:https://www.mdpi.com/1422-0067/24/1/721

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