Nr6a1 controls Hox expression dynamics and is a master regulator of vertebrate trunk development

The authors identify Nuclear receptor subfamily 6 group A member 1 (Nr6a1) as a master regulator of elongation, segmentation, patterning and lineage allocation specifically within the trunk region of the mouse, acting downstream of the major signals known to control vertebral column formation.

Dettagli Bibliografici
Autori principali: Yi-Cheng Chang, Jan Manent, Jan Schroeder, Siew Fen Lisa Wong, Gabriel M. Hauswirth, Natalia A. Shylo, Emma L. Moore, Annita Achilleos, Victoria Garside, Jose M. Polo, Paul Trainor, Edwina McGlinn
Natura: Articolo
Lingua:English
Pubblicazione: Nature Portfolio 2022-12-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-022-35303-4
Descrizione
Riassunto:The authors identify Nuclear receptor subfamily 6 group A member 1 (Nr6a1) as a master regulator of elongation, segmentation, patterning and lineage allocation specifically within the trunk region of the mouse, acting downstream of the major signals known to control vertebral column formation.
ISSN:2041-1723