Development of Tat-Conjugated Dendrimer for Transdermal DNA Vaccine Delivery

Development of Tat-Conjugated Dendrimer for Transdermal DNA Vaccine Delivery

PURPOSE: In order to enhance cellular uptake and to facilitate transdermal delivery of DNA vaccine, polyamidoamine (PAMAM) dendrimers conjugated with HIV transactivator of transcription (TAT) was developed. METHODS: First, the plasmid DNA (pIRES-H5/GFP) nanoparticle was formulated using PAMAM dendri...

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Bibliographic Details
Main Authors:	Azadeh Bahadoran, Hassan Moeini, Mohd Hair Bejo, Mohd Zobir Hussein, Abdul Rahman Omar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-08-01
Series:	Journal of Pharmacy & Pharmaceutical Sciences
Online Access:	https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/27766

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