Class A CpG oligodeoxynucleotide inhibits IFN‐γ‐induced signaling and apoptosis in lung cancer

Class A CpG oligodeoxynucleotide inhibits IFN‐γ‐induced signaling and apoptosis in lung cancer

Abstract Background Currently, anticancer immunotherapy based on PD‐1/PD‐L1 blockade with immune checkpoint inhibitors (ICIs) is being used as a standard therapy for non‐small cell lung cancer (NSCLC). However, more effective treatments are required as these tumors are often resistant and refractory...

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Main Authors: Shuhei Teranishi, Nobuaki Kobayashi, Seigo Katakura, Chisato Kamimaki, Sousuke Kubo, Yuji Shibata, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Thoracic Cancer
Subjects:
Apoptosis
CpG oligodeoxynucleotide
interferon‐γ
non‐small cell lung cancer
polyguanosine
Online Access:https://doi.org/10.1111/1759-7714.13351

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