Distinct plasma chemokines and cytokines signatures in Leishmania guyanensis-infected patients with cutaneous leishmaniasis

The immunopathology associated with Leishmaniasis is a consequence of inflammation. Upon infection with Leishmania, the type of host-immune response is determinant for the clinical manifestations that can lead to either self-healing or chronic disease. Multiple pathways may determine disease severit...

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Main Authors: Tirza Gabrielle Ramos de Mesquita, José do Espírito Santo Junior, Luan Diego Oliveira da Silva, George Allan Villarouco Silva, Felipe Jules de Araújo, Suzana Kanawati Pinheiro, Herllon Karllos Athaydes Kerr, Lener Santos da Silva, Luciane Macedo de Souza, Samir Assad de Almeida, Krys Layane Guimarães Duarte Queiroz, Josué Lacerda de Souza, Cilana Chagas da Silva, Héctor David Graterol Sequera, Mara Lúcia Gomes de Souza, Anderson Nogueira Barbosa, Gemilson Soares Pontes, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.974051/full