Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a global health problem, mainly in developing countries. It affects pulmonary blood vessels, right ventricle, and also left ventricle leading to pulmonary hypertension, cor pulmonale and right and left ventricular dysfunction. Aim: To as...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2022-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/15907/50524_CE[Ra1]_F[SH]_PF1(AG_KM)_PFA(AG_KM)_PN(KM).pdf |
| _version_ | 1811175379878019072 |
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| author | Keertivardhan D Kulkarni PA Mahesh |
| author_facet | Keertivardhan D Kulkarni PA Mahesh |
| author_sort | Keertivardhan D Kulkarni |
| collection | DOAJ |
| description | Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a global health problem, mainly in developing countries. It affects pulmonary blood vessels, right ventricle, and also left ventricle leading to pulmonary hypertension, cor pulmonale and right and left ventricular dysfunction.
Aim: To assess the cardiac, right and left ventricular changes in subjects with increasing COPD severity staged according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines and to compare Arterial Blood Gases (ABG), St. George’s Respiratory Questionnaire (SGRQ) percentages and BODE (Body-mass index, airflow Obstruction, Dyspnoea, and Exercise) scores to cardiac changes in COPD.
Materials and Methods: The present study was a cross-sectional study conducted at tertiary care hospital in Southern Karnataka, India. The sample size was 60. A structured questionnaire was administered which included demographic, clinical variables followed by a detailed clinical examination, spirometry, Electrocardiograph (ECG), ABG, chest radiograph, echocardiography and a 6-Minute Walk Test (6MWT). Data collected was analysed using Statistical Package for the Social Sciences (SPSS) and Epi Info software for mean, Standard Deviation (SD) and multivariate analysis.
Results: All the patients diagnosed with COPD (using GOLD criteria) were included in study and assessed for right and left ventricular changes. Out of 60 patients, 58 were males and two were females, with mean age being 64.71±28.28 years. Among the study population, 45 (75%) patients had one or the other cardiac condition. Cardiac changes included left ventricular diastolic dysfunction (58.3%), right ventricular dilatation (33.3%), right ventricular hypertrophy, right atrial dilation, tricuspid regurgitation and pulmonary hypertension and left heart changes included left ventricular hypertrophy.
Conclusion: The study highlights the need for early and active cardiac screening of all COPD patients. This will help in early treatment and good prognosis, and will further contribute in reducing the morbidity and mortality. |
| first_indexed | 2024-04-10T19:36:14Z |
| format | Article |
| id | doaj.art-11863efb8b9b477c8480ba91495fe78d |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T19:36:14Z |
| publishDate | 2022-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-11863efb8b9b477c8480ba91495fe78d2023-01-30T05:12:53ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-01-01161OC20OC2310.7860/JCDR/2022/50524.15907Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional StudyKeertivardhan D Kulkarni0PA Mahesh1Associate Professor, Department of Respiratory Medicine, BLDE (DU) Shri B M Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.Professor, Department of Respiratory Medicine, JSS Medical College, Mysuru, Karnataka, India.Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a global health problem, mainly in developing countries. It affects pulmonary blood vessels, right ventricle, and also left ventricle leading to pulmonary hypertension, cor pulmonale and right and left ventricular dysfunction. Aim: To assess the cardiac, right and left ventricular changes in subjects with increasing COPD severity staged according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines and to compare Arterial Blood Gases (ABG), St. George’s Respiratory Questionnaire (SGRQ) percentages and BODE (Body-mass index, airflow Obstruction, Dyspnoea, and Exercise) scores to cardiac changes in COPD. Materials and Methods: The present study was a cross-sectional study conducted at tertiary care hospital in Southern Karnataka, India. The sample size was 60. A structured questionnaire was administered which included demographic, clinical variables followed by a detailed clinical examination, spirometry, Electrocardiograph (ECG), ABG, chest radiograph, echocardiography and a 6-Minute Walk Test (6MWT). Data collected was analysed using Statistical Package for the Social Sciences (SPSS) and Epi Info software for mean, Standard Deviation (SD) and multivariate analysis. Results: All the patients diagnosed with COPD (using GOLD criteria) were included in study and assessed for right and left ventricular changes. Out of 60 patients, 58 were males and two were females, with mean age being 64.71±28.28 years. Among the study population, 45 (75%) patients had one or the other cardiac condition. Cardiac changes included left ventricular diastolic dysfunction (58.3%), right ventricular dilatation (33.3%), right ventricular hypertrophy, right atrial dilation, tricuspid regurgitation and pulmonary hypertension and left heart changes included left ventricular hypertrophy. Conclusion: The study highlights the need for early and active cardiac screening of all COPD patients. This will help in early treatment and good prognosis, and will further contribute in reducing the morbidity and mortality.https://www.jcdr.net/articles/PDF/15907/50524_CE[Ra1]_F[SH]_PF1(AG_KM)_PFA(AG_KM)_PN(KM).pdfchronic obstructive pulmonary diseasepulmonary hypertensionst. george’s respiratory questionnairetricuspid regurgitation |
| spellingShingle | Keertivardhan D Kulkarni PA Mahesh Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study Journal of Clinical and Diagnostic Research chronic obstructive pulmonary disease pulmonary hypertension st. george’s respiratory questionnaire tricuspid regurgitation |
| title | Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study |
| title_full | Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study |
| title_fullStr | Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study |
| title_full_unstemmed | Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study |
| title_short | Left Ventricular and Right Ventricular Functional Changes in Cases of COPD and its Correlation with Severity- A Cross-sectional Study |
| title_sort | left ventricular and right ventricular functional changes in cases of copd and its correlation with severity a cross sectional study |
| topic | chronic obstructive pulmonary disease pulmonary hypertension st. george’s respiratory questionnaire tricuspid regurgitation |
| url | https://www.jcdr.net/articles/PDF/15907/50524_CE[Ra1]_F[SH]_PF1(AG_KM)_PFA(AG_KM)_PN(KM).pdf |
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