Integrating between-host transmission and within-host immunity to analyze the impact of varicella vaccination on zoster
Varicella-zoster virus (VZV) causes chickenpox and reactivation of latent VZV causes herpes zoster (HZ). VZV reactivation is subject to the opposing mechanisms of declining and boosted VZV-specific cellular mediated immunity (CMI). A reduction in exogenous re-exposure ‘opportunities’ through univers...
Main Authors: | Benson Ogunjimi, Lander Willem, Philippe Beutels, Niel Hens |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/07116 |
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