Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis
Objective: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management. Methods: Study Design: Case Report Setting: Tertiary Government Hospital Patient: One Results: A 54-year-old w...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Philippine Society of Otolaryngology-Head and Neck Surgery, Inc.
2015-06-01
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| Series: | Philippine Journal of Otolaryngology Head and Neck Surgery |
| Subjects: | |
| Online Access: | https://pjohns.pso-hns.org/index.php/pjohns/article/view/395 |
| _version_ | 1818085015785832448 |
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| author | Ma. Melizza S. Villalon Celso V. Ureta |
| author_facet | Ma. Melizza S. Villalon Celso V. Ureta |
| author_sort | Ma. Melizza S. Villalon |
| collection | DOAJ |
| description | Objective: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management.
Methods:
Study Design: Case Report
Setting: Tertiary Government Hospital
Patient: One
Results: A 54-year-old woman presented with a 3-year history of recurrent nephrolithiasis despite several courses of shock wave lithotripsy. She had persistent hypercalcemia and parathyroid hormone levels were noted to be elevated. Neck ultrasound showed a hypoechoic solid nodule measuring approximately 1.7 x 1.6 cm in the lateral inferoposterior aspect of the left thyroid lobe. Parathyroid scintigraphy revealed a focal uptake on the left lower thyroidal bed. The patient underwent left inferior parathyroidectomy with subtotal thyroidectomy and isthmusectomy Frozen section reported a parathyroid tumor and the final histopathologic results revealed a parathyroid carcinoma.
Conclusion: A rare case of parathyroid carcinoma was presented, manifesting with recurrent nephrolithiasis. Elevated serum calcium and intact parathyroid hormone (iPTH) can confirm a primary hyperparathyroid problem. Neck ultrasound and parathyroid scintigraphy help in the localization of a parathyroid tumor. Only final histopathologic results can confirm the diagnosis of parathyroid carcinoma. Complete surgical excision is the treatment of choice and offers a good prognosis.
Keywords: Parathyroid carcinoma, primary hyperparathyroidism |
| first_indexed | 2024-12-10T20:03:04Z |
| format | Article |
| id | doaj.art-1187d772a7724e4fa6d7b8eedb81b925 |
| institution | Directory Open Access Journal |
| issn | 1908-4889 2094-1501 |
| language | English |
| last_indexed | 2024-12-10T20:03:04Z |
| publishDate | 2015-06-01 |
| publisher | Philippine Society of Otolaryngology-Head and Neck Surgery, Inc. |
| record_format | Article |
| series | Philippine Journal of Otolaryngology Head and Neck Surgery |
| spelling | doaj.art-1187d772a7724e4fa6d7b8eedb81b9252022-12-22T01:35:27ZengPhilippine Society of Otolaryngology-Head and Neck Surgery, Inc.Philippine Journal of Otolaryngology Head and Neck Surgery1908-48892094-15012015-06-0130110.32412/pjohns.v30i1.395Parathyroid Carcinoma Manifesting as Recurrent NephrolithiasisMa. Melizza S. Villalon0Celso V. Ureta1Department of Otorhinolaryngology Head and Neck Surgery Veterans Memorial Medical CenterDepartment of Otorhinolaryngology Head and Neck Surgery Veterans Memorial Medical CenterObjective: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management. Methods: Study Design: Case Report Setting: Tertiary Government Hospital Patient: One Results: A 54-year-old woman presented with a 3-year history of recurrent nephrolithiasis despite several courses of shock wave lithotripsy. She had persistent hypercalcemia and parathyroid hormone levels were noted to be elevated. Neck ultrasound showed a hypoechoic solid nodule measuring approximately 1.7 x 1.6 cm in the lateral inferoposterior aspect of the left thyroid lobe. Parathyroid scintigraphy revealed a focal uptake on the left lower thyroidal bed. The patient underwent left inferior parathyroidectomy with subtotal thyroidectomy and isthmusectomy Frozen section reported a parathyroid tumor and the final histopathologic results revealed a parathyroid carcinoma. Conclusion: A rare case of parathyroid carcinoma was presented, manifesting with recurrent nephrolithiasis. Elevated serum calcium and intact parathyroid hormone (iPTH) can confirm a primary hyperparathyroid problem. Neck ultrasound and parathyroid scintigraphy help in the localization of a parathyroid tumor. Only final histopathologic results can confirm the diagnosis of parathyroid carcinoma. Complete surgical excision is the treatment of choice and offers a good prognosis. Keywords: Parathyroid carcinoma, primary hyperparathyroidismhttps://pjohns.pso-hns.org/index.php/pjohns/article/view/395Parathyroid carcinoma, primary hyperparathyroidism |
| spellingShingle | Ma. Melizza S. Villalon Celso V. Ureta Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis Philippine Journal of Otolaryngology Head and Neck Surgery Parathyroid carcinoma, primary hyperparathyroidism |
| title | Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis |
| title_full | Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis |
| title_fullStr | Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis |
| title_full_unstemmed | Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis |
| title_short | Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis |
| title_sort | parathyroid carcinoma manifesting as recurrent nephrolithiasis |
| topic | Parathyroid carcinoma, primary hyperparathyroidism |
| url | https://pjohns.pso-hns.org/index.php/pjohns/article/view/395 |
| work_keys_str_mv | AT mamelizzasvillalon parathyroidcarcinomamanifestingasrecurrentnephrolithiasis AT celsovureta parathyroidcarcinomamanifestingasrecurrentnephrolithiasis |