Knockout of KLF10 Ameliorated Diabetic Renal Fibrosis via Downregulation of DKK-1

Knockout of KLF10 Ameliorated Diabetic Renal Fibrosis via Downregulation of DKK-1

Diabetes-induced chronic kidney disease leads to mortality and morbidity and thus poses a great health burden worldwide. Krüppel-like factor 10 (KLF10), a zinc finger-containing transcription factor, regulates numerous cellular functions, such as proliferation, differentiation, and apoptosis. In thi...

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Bibliographic Details
Main Authors: Yung-Chien Hsu, Cheng Ho, Ya-Hsueh Shih, Wen-Chiu Ni, Yi-Chen Li, Hsiu-Ching Chang, Chun-Liang Lin
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
diabetes
renal fibrosis
KLF10
DKK-1
Online Access:https://www.mdpi.com/1420-3049/27/9/2644

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