Immune cell responses in pancreatic cancer and their clinical application
Pancreatic cancer is one of the most lethal diseases around the world, for hardly detection and poor prognosis. Recent years, functions of the tumor microenvironment and immune cells attract people’s view and there is emerging evidence implicating some immune cells hold the key points in the metabol...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-01-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/20587392211044381 |
| _version_ | 1828822710531129344 |
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| author | Xulin Zhou Yongmin Yan Min Xu |
| author_facet | Xulin Zhou Yongmin Yan Min Xu |
| author_sort | Xulin Zhou |
| collection | DOAJ |
| description | Pancreatic cancer is one of the most lethal diseases around the world, for hardly detection and poor prognosis. Recent years, functions of the tumor microenvironment and immune cells attract people’s view and there is emerging evidence implicating some immune cells hold the key points in the metabolism, invasion, and metastasis in pancreatic cancer. In this review, we highlight some main immune cells, such as Tumor-associated neutrophils (TANs) and macrophages (TAMs), Pancreatic stellate cells (PSCs), Myeloid-derived suppressor cells (MDSCs), and Regulatory T cells (Tregs). Furthermore, we review current clinical applications and discuss potential values in future. |
| first_indexed | 2024-12-12T13:18:59Z |
| format | Article |
| id | doaj.art-118d9783e4d24239848c7e5a00578977 |
| institution | Directory Open Access Journal |
| issn | 2058-7392 |
| language | English |
| last_indexed | 2024-12-12T13:18:59Z |
| publishDate | 2022-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | European Journal of Inflammation |
| spelling | doaj.art-118d9783e4d24239848c7e5a005789772022-12-22T00:23:20ZengSAGE PublishingEuropean Journal of Inflammation2058-73922022-01-012010.1177/20587392211044381Immune cell responses in pancreatic cancer and their clinical applicationXulin ZhouYongmin YanMin XuPancreatic cancer is one of the most lethal diseases around the world, for hardly detection and poor prognosis. Recent years, functions of the tumor microenvironment and immune cells attract people’s view and there is emerging evidence implicating some immune cells hold the key points in the metabolism, invasion, and metastasis in pancreatic cancer. In this review, we highlight some main immune cells, such as Tumor-associated neutrophils (TANs) and macrophages (TAMs), Pancreatic stellate cells (PSCs), Myeloid-derived suppressor cells (MDSCs), and Regulatory T cells (Tregs). Furthermore, we review current clinical applications and discuss potential values in future.https://doi.org/10.1177/20587392211044381 |
| spellingShingle | Xulin Zhou Yongmin Yan Min Xu Immune cell responses in pancreatic cancer and their clinical application European Journal of Inflammation |
| title | Immune cell responses in pancreatic cancer and their clinical application |
| title_full | Immune cell responses in pancreatic cancer and their clinical application |
| title_fullStr | Immune cell responses in pancreatic cancer and their clinical application |
| title_full_unstemmed | Immune cell responses in pancreatic cancer and their clinical application |
| title_short | Immune cell responses in pancreatic cancer and their clinical application |
| title_sort | immune cell responses in pancreatic cancer and their clinical application |
| url | https://doi.org/10.1177/20587392211044381 |
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