Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract
The objective of the study is to synthesis silver nanoparticles from the leaf extract of Cryptolepis buchanani, a medically important plant,by green synthesis method. The synthesized nanoparticles have an average size of 17.05±5.27 nm, crystalline in nature with face cantered cubic structure, and po...
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| Format: | Article |
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Iranian Society of Nanomedicine
2020-11-01
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| Series: | Nanomedicine Research Journal |
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| Online Access: | http://www.nanomedicine-rj.com/article_47991_a5b5210f2e1d111b862c55db5a57e179.pdf |
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| author | Sudipta Panja Anutosh Patra Kalyani Khanra Indranil Choudhuri Bikash Pati Nandan Bhattacharyya |
| author_facet | Sudipta Panja Anutosh Patra Kalyani Khanra Indranil Choudhuri Bikash Pati Nandan Bhattacharyya |
| author_sort | Sudipta Panja |
| collection | DOAJ |
| description | The objective of the study is to synthesis silver nanoparticles from the leaf extract of Cryptolepis buchanani, a medically important plant,by green synthesis method. The synthesized nanoparticles have an average size of 17.05±5.27 nm, crystalline in nature with face cantered cubic structure, and positive surface charge. The nanoparticles are biologically active. It killed > 90 % of HeLa cells at 25 μg mL-1 concentration in-vitro cell cytotoxicity assay, with a LD50 value of 3.98 μg mL-1. The nanoparticles are less effective on MCF-7 and HEK-293 cell line, almost 70 % of MCF-7 populations were survived at highest concentration of 25 μg mL-1. In case of HEK-293 it killed almost 78 % of cells at the same concentration with a 9.45 μg mL-1 LD50 value. The synthesized nanoparticle lysed less than 2.5 % of red blood cells at 10 μg mL-1 concentration in-vitro. The nanoparticles degraded >90 % of methylene blue dye in presence of light in 8.5 h. These properties of the synthesized nanoparticles are unique, and make it promising for its future potential applications. |
| first_indexed | 2024-04-11T19:12:56Z |
| format | Article |
| id | doaj.art-118f9c620a74418cae7a287852809a9d |
| institution | Directory Open Access Journal |
| issn | 2476-3489 2476-7123 |
| language | English |
| last_indexed | 2024-04-11T19:12:56Z |
| publishDate | 2020-11-01 |
| publisher | Iranian Society of Nanomedicine |
| record_format | Article |
| series | Nanomedicine Research Journal |
| spelling | doaj.art-118f9c620a74418cae7a287852809a9d2022-12-22T04:07:33ZengIranian Society of NanomedicineNanomedicine Research Journal2476-34892476-71232020-11-015436937710.22034/nmrj.2020.04.00947991Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extractSudipta Panja0Anutosh Patra1Kalyani Khanra2Indranil Choudhuri3Bikash Pati4Nandan Bhattacharyya5Department of Biotechnology, Panskura Banamali College, P.O. – Panskura R.S., Purba Medinipur, West Bengal, PIN- 721152, IndiaDepartment of Biotechnology, Panskura Banamali College, P.O. – Panskura R.S., Purba Medinipur, West Bengal, PIN- 721152, IndiaDepartment of Biotechnology, Panskura Banamali College, P.O. – Panskura R.S., Purba Medinipur, West Bengal, PIN- 721152, IndiaDepartment of Biotechnology, Panskura Banamali College, P.O. – Panskura R.S., Purba Medinipur, West Bengal, PIN- 721152, IndiaDepartment of Microbiology, Vidyasagar University, Medinipur, West Bengal, PIN - 721102, IndiaDepartment of Biotechnology, Panskura Banamali College, P.O. – Panskura R.S., Purba Medinipur, West Bengal, PIN- 721152, IndiaThe objective of the study is to synthesis silver nanoparticles from the leaf extract of Cryptolepis buchanani, a medically important plant,by green synthesis method. The synthesized nanoparticles have an average size of 17.05±5.27 nm, crystalline in nature with face cantered cubic structure, and positive surface charge. The nanoparticles are biologically active. It killed > 90 % of HeLa cells at 25 μg mL-1 concentration in-vitro cell cytotoxicity assay, with a LD50 value of 3.98 μg mL-1. The nanoparticles are less effective on MCF-7 and HEK-293 cell line, almost 70 % of MCF-7 populations were survived at highest concentration of 25 μg mL-1. In case of HEK-293 it killed almost 78 % of cells at the same concentration with a 9.45 μg mL-1 LD50 value. The synthesized nanoparticle lysed less than 2.5 % of red blood cells at 10 μg mL-1 concentration in-vitro. The nanoparticles degraded >90 % of methylene blue dye in presence of light in 8.5 h. These properties of the synthesized nanoparticles are unique, and make it promising for its future potential applications.http://www.nanomedicine-rj.com/article_47991_a5b5210f2e1d111b862c55db5a57e179.pdfcryptolepis buchananisilver nanoparticlegreen synthesiscytotoxicityphotocatalytic activity |
| spellingShingle | Sudipta Panja Anutosh Patra Kalyani Khanra Indranil Choudhuri Bikash Pati Nandan Bhattacharyya Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract Nanomedicine Research Journal cryptolepis buchanani silver nanoparticle green synthesis cytotoxicity photocatalytic activity |
| title | Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract |
| title_full | Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract |
| title_fullStr | Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract |
| title_full_unstemmed | Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract |
| title_short | Bio efficacy, and photocatalytic activity of the silver nanoparticles synthesized from Cryptolepis buchanani leaf extract |
| title_sort | bio efficacy and photocatalytic activity of the silver nanoparticles synthesized from cryptolepis buchanani leaf extract |
| topic | cryptolepis buchanani silver nanoparticle green synthesis cytotoxicity photocatalytic activity |
| url | http://www.nanomedicine-rj.com/article_47991_a5b5210f2e1d111b862c55db5a57e179.pdf |
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