Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age
ABSTRACT: Colostrum consumption is crucial for passive immunization and development of the newborn calf. However, the incidence on failed transfer of passive immunity in male calves destined to dairy-beef production remains high to date. In addition, the lack of an automated procedure to validate th...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Journal of Dairy Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022030222006816 |
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| author | L. Pisoni S. Marti J. Pujols Y. Saco N. Gomez A. Bassols M. Devant |
| author_facet | L. Pisoni S. Marti J. Pujols Y. Saco N. Gomez A. Bassols M. Devant |
| author_sort | L. Pisoni |
| collection | DOAJ |
| description | ABSTRACT: Colostrum consumption is crucial for passive immunization and development of the newborn calf. However, the incidence on failed transfer of passive immunity in male calves destined to dairy-beef production remains high to date. In addition, the lack of an automated procedure to validate the immunization status upon arrival at rearing facilities in calves beyond 14 d of age impedes the identification of failed transfer of passive immunity, and therefore, of those calves at high risk of suffering diseases. For this study, 82 newborn male Holstein calves (43.3 ± 0.86 kg of body weight; mean ± standard error) from a commercial dairy farm were used to investigate potential serum biomarkers of colostrum provision. The potential biomarkers selected were IgG, IgG1, cholesterol, alkaline phosphatase, gamma-glutamyl transferase (GGT), and total protein (TP). Treatments were as follows: high-colostrum (HC; n = 49), in which calves received 4 L of colostrum within the first 2 h after birth and 2 L of colostrum in the next 3 feedings within the first 24 h after birth, for a total of 10 L of colostrum; and low-colostrum (LC; n = 33), in which calves received only 2 L of colostrum within the first 2 h after birth. After colostrum consumption, calves were allocated to individual hutches and fed 2 L of milk replacer twice daily at a concentration of 125 g/L as fed. Starter feed and water were offered ad libitum. At approximately 14 d of age (14.2 ± 0.81 d of age; mean ± standard error) calves were transported 2.5 h to a research unit at IRTA (Torre Marimon, Spain) simulating the arrival to a rearing facility. Blood samples were collected before feeding at birth, 48 h after birth, and at arrival to the rearing facility. Results on the serum concentrations of the potential biomarkers at arrival to the rearing facility showed that IgG, IgG1, GGT, and TP were greater for the HC calves compared with the LC calves. Serum concentrations of cholesterol and alkaline phosphatase did not show differences between treatment groups. Additionally, body weight losses from birth until arrival to the rearing facility were greater for the LC treatment compared with the HC. Because of their low cost, quickness, and ease of measurement, GGT and TP were good indicators of colostrum intake in calves arriving at rearing facilities beyond 14 d of age. |
| first_indexed | 2024-04-13T04:39:19Z |
| format | Article |
| id | doaj.art-11900e6b5eea4959899528695e2e413e |
| institution | Directory Open Access Journal |
| issn | 0022-0302 |
| language | English |
| last_indexed | 2024-04-13T04:39:19Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Dairy Science |
| spelling | doaj.art-11900e6b5eea4959899528695e2e413e2022-12-22T03:02:04ZengElsevierJournal of Dairy Science0022-03022023-01-011061743754Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of ageL. Pisoni0S. Marti1J. Pujols2Y. Saco3N. Gomez4A. Bassols5M. Devant6Department of Ruminant Production, IRTA (Institut de Recerca i Tecnologies Agroalimentàries), Torre Marimon, Caldes de Montbui, SpainDepartment of Ruminant Production, IRTA (Institut de Recerca i Tecnologies Agroalimentàries), Torre Marimon, Caldes de Montbui, Spain; Corresponding authorsAnimal Health Research Center (CReSA), UAB-IRTA, Universitat Autònoma de Barcelona, Cerdanyola del Valles, SpainDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Science, Universitat Autònoma de Barcelona, Cerdanyola del Valles, SpainDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Science, Universitat Autònoma de Barcelona, Cerdanyola del Valles, SpainDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Science, Universitat Autònoma de Barcelona, Cerdanyola del Valles, SpainDepartment of Ruminant Production, IRTA (Institut de Recerca i Tecnologies Agroalimentàries), Torre Marimon, Caldes de Montbui, Spain; Corresponding authorsABSTRACT: Colostrum consumption is crucial for passive immunization and development of the newborn calf. However, the incidence on failed transfer of passive immunity in male calves destined to dairy-beef production remains high to date. In addition, the lack of an automated procedure to validate the immunization status upon arrival at rearing facilities in calves beyond 14 d of age impedes the identification of failed transfer of passive immunity, and therefore, of those calves at high risk of suffering diseases. For this study, 82 newborn male Holstein calves (43.3 ± 0.86 kg of body weight; mean ± standard error) from a commercial dairy farm were used to investigate potential serum biomarkers of colostrum provision. The potential biomarkers selected were IgG, IgG1, cholesterol, alkaline phosphatase, gamma-glutamyl transferase (GGT), and total protein (TP). Treatments were as follows: high-colostrum (HC; n = 49), in which calves received 4 L of colostrum within the first 2 h after birth and 2 L of colostrum in the next 3 feedings within the first 24 h after birth, for a total of 10 L of colostrum; and low-colostrum (LC; n = 33), in which calves received only 2 L of colostrum within the first 2 h after birth. After colostrum consumption, calves were allocated to individual hutches and fed 2 L of milk replacer twice daily at a concentration of 125 g/L as fed. Starter feed and water were offered ad libitum. At approximately 14 d of age (14.2 ± 0.81 d of age; mean ± standard error) calves were transported 2.5 h to a research unit at IRTA (Torre Marimon, Spain) simulating the arrival to a rearing facility. Blood samples were collected before feeding at birth, 48 h after birth, and at arrival to the rearing facility. Results on the serum concentrations of the potential biomarkers at arrival to the rearing facility showed that IgG, IgG1, GGT, and TP were greater for the HC calves compared with the LC calves. Serum concentrations of cholesterol and alkaline phosphatase did not show differences between treatment groups. Additionally, body weight losses from birth until arrival to the rearing facility were greater for the LC treatment compared with the HC. Because of their low cost, quickness, and ease of measurement, GGT and TP were good indicators of colostrum intake in calves arriving at rearing facilities beyond 14 d of age.http://www.sciencedirect.com/science/article/pii/S0022030222006816dairy-beef calfcolostrum provisiongamma-glutamyl transferasetotal protein |
| spellingShingle | L. Pisoni S. Marti J. Pujols Y. Saco N. Gomez A. Bassols M. Devant Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age Journal of Dairy Science dairy-beef calf colostrum provision gamma-glutamyl transferase total protein |
| title | Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age |
| title_full | Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age |
| title_fullStr | Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age |
| title_full_unstemmed | Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age |
| title_short | Evaluation of potential biomarkers to determine adequate colostrum provision in male dairy-beef calves upon arrival at the rearing facility beyond 14 days of age |
| title_sort | evaluation of potential biomarkers to determine adequate colostrum provision in male dairy beef calves upon arrival at the rearing facility beyond 14 days of age |
| topic | dairy-beef calf colostrum provision gamma-glutamyl transferase total protein |
| url | http://www.sciencedirect.com/science/article/pii/S0022030222006816 |
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