Current Concepts of Metastasis Formation
The development of secondary distant organ and lymph node metastasis has an extraordinary impact on the prognosis of patients with solid cancer. In most cases the advent of metastatic growth represents the turning point from a local, potentially curable, disease to a systemic non-curable situation....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-07-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-6694/3/3/2886/ |
| _version_ | 1797710681637650432 |
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| author | Peter Gassman Jörg Haier |
| author_facet | Peter Gassman Jörg Haier |
| author_sort | Peter Gassman |
| collection | DOAJ |
| description | The development of secondary distant organ and lymph node metastasis has an extraordinary impact on the prognosis of patients with solid cancer. In most cases the advent of metastatic growth represents the turning point from a local, potentially curable, disease to a systemic non-curable situation. As a highly regulated process, metastasis formation follows a distinct, non-random pattern characteristic for each tumor entity. Metastasis formation and strategies to prevent this lethal event in the progression of cancer is of fundamental interest for cancer science and patient care. In this special issue of Cancers, papers highlighting cellular mechanisms of metastasis formation, genetic and epigenetic aspects associated with organ and tumor specific metastasis formation, as well as papers outlining experimental and clinical therapeutic concepts for anti-metastatic treatment are included. |
| first_indexed | 2024-03-12T06:55:45Z |
| format | Article |
| id | doaj.art-1190e063209e4508a3ebab406edfb2a1 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T06:55:45Z |
| publishDate | 2011-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-1190e063209e4508a3ebab406edfb2a12023-09-03T00:02:23ZengMDPI AGCancers2072-66942011-07-01332886288710.3390/cancers3032886Current Concepts of Metastasis FormationPeter GassmanJörg HaierThe development of secondary distant organ and lymph node metastasis has an extraordinary impact on the prognosis of patients with solid cancer. In most cases the advent of metastatic growth represents the turning point from a local, potentially curable, disease to a systemic non-curable situation. As a highly regulated process, metastasis formation follows a distinct, non-random pattern characteristic for each tumor entity. Metastasis formation and strategies to prevent this lethal event in the progression of cancer is of fundamental interest for cancer science and patient care. In this special issue of Cancers, papers highlighting cellular mechanisms of metastasis formation, genetic and epigenetic aspects associated with organ and tumor specific metastasis formation, as well as papers outlining experimental and clinical therapeutic concepts for anti-metastatic treatment are included.http://www.mdpi.com/2072-6694/3/3/2886/n/a |
| spellingShingle | Peter Gassman Jörg Haier Current Concepts of Metastasis Formation Cancers n/a |
| title | Current Concepts of Metastasis Formation |
| title_full | Current Concepts of Metastasis Formation |
| title_fullStr | Current Concepts of Metastasis Formation |
| title_full_unstemmed | Current Concepts of Metastasis Formation |
| title_short | Current Concepts of Metastasis Formation |
| title_sort | current concepts of metastasis formation |
| topic | n/a |
| url | http://www.mdpi.com/2072-6694/3/3/2886/ |
| work_keys_str_mv | AT petergassman currentconceptsofmetastasisformation AT jorghaier currentconceptsofmetastasisformation |