Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals
Several chemicals have been developed owing to the progression of industrialization, among which endocrine-disrupting chemicals (EDCs; essential for plastic production) are used as plasticizers and flame retardants. Plastics have become an essential element in modern life because they provide conven...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Journal of Ginseng Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1226845322001543 |
| _version_ | 1811162713955500032 |
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| author | Eui-Man Jung Seung Hyun Lee Geun-Shik Lee |
| author_facet | Eui-Man Jung Seung Hyun Lee Geun-Shik Lee |
| author_sort | Eui-Man Jung |
| collection | DOAJ |
| description | Several chemicals have been developed owing to the progression of industrialization, among which endocrine-disrupting chemicals (EDCs; essential for plastic production) are used as plasticizers and flame retardants. Plastics have become an essential element in modern life because they provide convenience, thus increasing EDCs exposure to humans. EDCs cause adverse effects such as deterioration of reproductive function, cancer, and neurological abnormalities by disrupting the endocrine system and hence are classified as “dangerous substances.” Additionally, they are toxic to various organs but continue to be used. Therefore, it is necessary to review the contamination status of EDCs, select potentially hazardous substances for management, and monitor the safety standards. In addition, it is necessary to discover substances that can protect against EDC toxicity and conduct active research on the protective effects of these substances. According to recent research, Korean Red Ginseng (KRG) exhibits protective effects against several toxicities caused by EDCs to humans. In this review, the effects of EDCs on the human body and the role of KRG in protection against EDC toxicity are discussed. |
| first_indexed | 2024-04-10T06:33:39Z |
| format | Article |
| id | doaj.art-119221c8d4954cd2880b260b20719551 |
| institution | Directory Open Access Journal |
| issn | 1226-8453 |
| language | English |
| last_indexed | 2024-04-10T06:33:39Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Ginseng Research |
| spelling | doaj.art-119221c8d4954cd2880b260b207195512023-03-01T04:31:14ZengElsevierJournal of Ginseng Research1226-84532023-03-01472193198Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicalsEui-Man Jung0Seung Hyun Lee1Geun-Shik Lee2Department of Molecular Biology, College of Natural Sciences, Pusan National University, Busan, Republic of Korea; Corresponding author. Department of Molecular Biology, College of Natural Sciences, Pusan National University, Busan, 46241, Republic of Korea.Department of Molecular Biology, College of Natural Sciences, Pusan National University, Busan, Republic of KoreaCollege of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Republic of Korea; Corresponding author. Laboratory of Inflammatory Diseases, Department of Physiology, College of Veterinary Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, 24341, Republic of Korea.Several chemicals have been developed owing to the progression of industrialization, among which endocrine-disrupting chemicals (EDCs; essential for plastic production) are used as plasticizers and flame retardants. Plastics have become an essential element in modern life because they provide convenience, thus increasing EDCs exposure to humans. EDCs cause adverse effects such as deterioration of reproductive function, cancer, and neurological abnormalities by disrupting the endocrine system and hence are classified as “dangerous substances.” Additionally, they are toxic to various organs but continue to be used. Therefore, it is necessary to review the contamination status of EDCs, select potentially hazardous substances for management, and monitor the safety standards. In addition, it is necessary to discover substances that can protect against EDC toxicity and conduct active research on the protective effects of these substances. According to recent research, Korean Red Ginseng (KRG) exhibits protective effects against several toxicities caused by EDCs to humans. In this review, the effects of EDCs on the human body and the role of KRG in protection against EDC toxicity are discussed.http://www.sciencedirect.com/science/article/pii/S1226845322001543Endocrine-disrupting chemicalsGinsenosidesKorean Red GinsengToxicity |
| spellingShingle | Eui-Man Jung Seung Hyun Lee Geun-Shik Lee Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals Journal of Ginseng Research Endocrine-disrupting chemicals Ginsenosides Korean Red Ginseng Toxicity |
| title | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
| title_full | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
| title_fullStr | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
| title_full_unstemmed | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
| title_short | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
| title_sort | protective effects of korean red ginseng against toxicity of endocrine disrupting chemicals |
| topic | Endocrine-disrupting chemicals Ginsenosides Korean Red Ginseng Toxicity |
| url | http://www.sciencedirect.com/science/article/pii/S1226845322001543 |
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