Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion

Objective: To assess the efficacy of bioactive glass, self-assembling peptide, and ozone-remineralizing agents on the artificial carious lesion. Material and Methods: On the extracted 60 premolar teeth, an artificial carious lesion/demineralization was created. Later, the remineralization of deminer...

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Main Authors: Noura Alessa, Shahzad Ali Shah, Rishibha Bhardwaj, Prabu Mahin Syed Ismail, M. Nazargi Mahabob, Prashant Babaji, Vardarajula Venkata Ramaiah
Format: Article
Language:English
Published: Association of Support to Oral Health Research (APESB) 2024-01-01
Series:Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Subjects:
Online Access:https://revista.uepb.edu.br/PBOCI/article/view/3110
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author Noura Alessa
Shahzad Ali Shah
Rishibha Bhardwaj
Prabu Mahin Syed Ismail
M. Nazargi Mahabob
Prashant Babaji
Vardarajula Venkata Ramaiah
author_facet Noura Alessa
Shahzad Ali Shah
Rishibha Bhardwaj
Prabu Mahin Syed Ismail
M. Nazargi Mahabob
Prashant Babaji
Vardarajula Venkata Ramaiah
author_sort Noura Alessa
collection DOAJ
description Objective: To assess the efficacy of bioactive glass, self-assembling peptide, and ozone-remineralizing agents on the artificial carious lesion. Material and Methods: On the extracted 60 premolar teeth, an artificial carious lesion/demineralization was created. Later, the remineralization of demineralized teeth was done with respective remineralizing agents (Group A: Calcium sodium phosphosilicate (bioactive glass), Group B: Self-assembling peptide, Group C: Ozone remineralizing agents and Group D (Control): De ionized water. The degree of demineralization and remineralization were evaluated using the Vickers Hardness Number. Results: There was a decrease in microhardness from baseline to demineralization in all the groups, and this reduction was found to be statistically considerable. After the remineralization of demineralized samples with respective remineralizing agents, there was an increase in microhardness of 312.38, 276.67, and 254.42 in groups A, B, and C, respectively. In contrast, in Group D, there were no changes. Conclusion: Bioactive glass and self-assembling peptides had higher remineralizing capacities, which can be used to treat early carious lesions.
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spelling doaj.art-119648af02644ee9b83272ef78dde80b2024-02-06T12:36:14ZengAssociation of Support to Oral Health Research (APESB)Pesquisa Brasileira em Odontopediatria e Clínica Integrada1519-05011983-46322024-01-0124Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious LesionNoura AlessaShahzad Ali ShahRishibha BhardwajPrabu Mahin Syed IsmailM. Nazargi MahabobPrashant BabajiVardarajula Venkata RamaiahObjective: To assess the efficacy of bioactive glass, self-assembling peptide, and ozone-remineralizing agents on the artificial carious lesion. Material and Methods: On the extracted 60 premolar teeth, an artificial carious lesion/demineralization was created. Later, the remineralization of demineralized teeth was done with respective remineralizing agents (Group A: Calcium sodium phosphosilicate (bioactive glass), Group B: Self-assembling peptide, Group C: Ozone remineralizing agents and Group D (Control): De ionized water. The degree of demineralization and remineralization were evaluated using the Vickers Hardness Number. Results: There was a decrease in microhardness from baseline to demineralization in all the groups, and this reduction was found to be statistically considerable. After the remineralization of demineralized samples with respective remineralizing agents, there was an increase in microhardness of 312.38, 276.67, and 254.42 in groups A, B, and C, respectively. In contrast, in Group D, there were no changes. Conclusion: Bioactive glass and self-assembling peptides had higher remineralizing capacities, which can be used to treat early carious lesions.https://revista.uepb.edu.br/PBOCI/article/view/3110Dental CariesEfficiencyDental EnamelOzone
spellingShingle Noura Alessa
Shahzad Ali Shah
Rishibha Bhardwaj
Prabu Mahin Syed Ismail
M. Nazargi Mahabob
Prashant Babaji
Vardarajula Venkata Ramaiah
Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion
Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Dental Caries
Efficiency
Dental Enamel
Ozone
title Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion
title_full Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion
title_fullStr Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion
title_full_unstemmed Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion
title_short Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion
title_sort assessment of efficiency of bioactive glass self assembling peptide and ozone remineralising agents on artificial carious lesion
topic Dental Caries
Efficiency
Dental Enamel
Ozone
url https://revista.uepb.edu.br/PBOCI/article/view/3110
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