How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
Possible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ul...
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Format: | Article |
Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2016-07-01
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Series: | Clinical Endoscopy |
Subjects: | |
Online Access: | http://www.e-ce.org/upload/pdf/ce-2016-082.pdf |
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author | Dae Young Cheung Soo-Heon Park |
author_facet | Dae Young Cheung Soo-Heon Park |
author_sort | Dae Young Cheung |
collection | DOAJ |
description | Possible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ulceration should be thoroughly evaluated before proceeding with ESD. However, with incomplete information, discrepancies often arise between the pathological diagnosis based on the forceps biopsy and that based on the totally resected specimen. In addition, the presence of lymphovascular involvement and histological homogeneity can be clarified only after ESD. If the pathological diagnosis changes after ESD, we should reevaluate the curativeness and reformulate the goal of treatment. Additional surgery is a reasonable strategy for non-curative ESD, but a patient’s other health conditions should also be considered. It is simple to read pathological reports before and after ESD, but it can be a complicated art to interpret the report and formulate an optimal approach. In this review, various considerations regarding the pathological diagnosis will be discussed. |
first_indexed | 2024-03-09T08:16:21Z |
format | Article |
id | doaj.art-119740cd96b849c88ce159f6bb1eef50 |
institution | Directory Open Access Journal |
issn | 2234-2400 2234-2443 |
language | English |
last_indexed | 2024-03-09T08:16:21Z |
publishDate | 2016-07-01 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | Article |
series | Clinical Endoscopy |
spelling | doaj.art-119740cd96b849c88ce159f6bb1eef502023-12-02T22:10:37ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432016-07-0149432733110.5946/ce.2016.0826894How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric CancerDae Young CheungSoo-Heon ParkPossible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ulceration should be thoroughly evaluated before proceeding with ESD. However, with incomplete information, discrepancies often arise between the pathological diagnosis based on the forceps biopsy and that based on the totally resected specimen. In addition, the presence of lymphovascular involvement and histological homogeneity can be clarified only after ESD. If the pathological diagnosis changes after ESD, we should reevaluate the curativeness and reformulate the goal of treatment. Additional surgery is a reasonable strategy for non-curative ESD, but a patient’s other health conditions should also be considered. It is simple to read pathological reports before and after ESD, but it can be a complicated art to interpret the report and formulate an optimal approach. In this review, various considerations regarding the pathological diagnosis will be discussed.http://www.e-ce.org/upload/pdf/ce-2016-082.pdfEndoscopic submucosal dissectionEarly gastric cancerPathology |
spellingShingle | Dae Young Cheung Soo-Heon Park How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer Clinical Endoscopy Endoscopic submucosal dissection Early gastric cancer Pathology |
title | How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer |
title_full | How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer |
title_fullStr | How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer |
title_full_unstemmed | How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer |
title_short | How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer |
title_sort | how to interpret the pathological report before and after endoscopic submucosal dissection of early gastric cancer |
topic | Endoscopic submucosal dissection Early gastric cancer Pathology |
url | http://www.e-ce.org/upload/pdf/ce-2016-082.pdf |
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