How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer

Possible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ul...

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Main Authors: Dae Young Cheung, Soo-Heon Park
Format: Article
Language:English
Published: Korean Society of Gastrointestinal Endoscopy 2016-07-01
Series:Clinical Endoscopy
Subjects:
Online Access:http://www.e-ce.org/upload/pdf/ce-2016-082.pdf
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author Dae Young Cheung
Soo-Heon Park
author_facet Dae Young Cheung
Soo-Heon Park
author_sort Dae Young Cheung
collection DOAJ
description Possible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ulceration should be thoroughly evaluated before proceeding with ESD. However, with incomplete information, discrepancies often arise between the pathological diagnosis based on the forceps biopsy and that based on the totally resected specimen. In addition, the presence of lymphovascular involvement and histological homogeneity can be clarified only after ESD. If the pathological diagnosis changes after ESD, we should reevaluate the curativeness and reformulate the goal of treatment. Additional surgery is a reasonable strategy for non-curative ESD, but a patient’s other health conditions should also be considered. It is simple to read pathological reports before and after ESD, but it can be a complicated art to interpret the report and formulate an optimal approach. In this review, various considerations regarding the pathological diagnosis will be discussed.
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spelling doaj.art-119740cd96b849c88ce159f6bb1eef502023-12-02T22:10:37ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432016-07-0149432733110.5946/ce.2016.0826894How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric CancerDae Young CheungSoo-Heon ParkPossible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ulceration should be thoroughly evaluated before proceeding with ESD. However, with incomplete information, discrepancies often arise between the pathological diagnosis based on the forceps biopsy and that based on the totally resected specimen. In addition, the presence of lymphovascular involvement and histological homogeneity can be clarified only after ESD. If the pathological diagnosis changes after ESD, we should reevaluate the curativeness and reformulate the goal of treatment. Additional surgery is a reasonable strategy for non-curative ESD, but a patient’s other health conditions should also be considered. It is simple to read pathological reports before and after ESD, but it can be a complicated art to interpret the report and formulate an optimal approach. In this review, various considerations regarding the pathological diagnosis will be discussed.http://www.e-ce.org/upload/pdf/ce-2016-082.pdfEndoscopic submucosal dissectionEarly gastric cancerPathology
spellingShingle Dae Young Cheung
Soo-Heon Park
How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
Clinical Endoscopy
Endoscopic submucosal dissection
Early gastric cancer
Pathology
title How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
title_full How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
title_fullStr How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
title_full_unstemmed How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
title_short How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer
title_sort how to interpret the pathological report before and after endoscopic submucosal dissection of early gastric cancer
topic Endoscopic submucosal dissection
Early gastric cancer
Pathology
url http://www.e-ce.org/upload/pdf/ce-2016-082.pdf
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