Volume-constrained microcontainers enable myoepithelial functional differentiation in highly parallel mammary organoid culture

Summary: A long-standing constraint on organoid culture is the need to add exogenous substances to provide hydrogel matrix, which limits the study of fully human or fully native organoids. This paper introduces an approach to culture reconstituted mammary organoids without the impediment of exogenou...

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Bibliographic Details
Main Authors: Michael E. Todhunter, Masaru Miyano, Divya S. Moolamalla, Aleksandr Filippov, Rosalyn W. Sayaman, Mark A. LaBarge
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002212