Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-03-01
|
| Series: | Signal Transduction and Targeted Therapy |
| Online Access: | https://doi.org/10.1038/s41392-021-00520-8 |
| _version_ | 1830089349219221504 |
|---|---|
| author | Yanli Wang Wenping Xie Bin Liu Hui Huang Wei Luo Yu Zhang Xiangbin Pan Xi-Yong Yu Zhenya Shen Yangxin Li |
| author_facet | Yanli Wang Wenping Xie Bin Liu Hui Huang Wei Luo Yu Zhang Xiangbin Pan Xi-Yong Yu Zhenya Shen Yangxin Li |
| author_sort | Yanli Wang |
| collection | DOAJ |
| first_indexed | 2024-12-16T16:43:18Z |
| format | Article |
| id | doaj.art-119a71507f5e40198cd33e58384ff70e |
| institution | Directory Open Access Journal |
| issn | 2059-3635 |
| language | English |
| last_indexed | 2024-12-16T16:43:18Z |
| publishDate | 2021-03-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Signal Transduction and Targeted Therapy |
| spelling | doaj.art-119a71507f5e40198cd33e58384ff70e2022-12-21T22:24:14ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352021-03-01611310.1038/s41392-021-00520-8Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathwayYanli Wang0Wenping Xie1Bin Liu2Hui Huang3Wei Luo4Yu Zhang5Xiangbin Pan6Xi-Yong Yu7Zhenya Shen8Yangxin Li9Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow UniversityInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow UniversityDepartment of Cardiology, The Second Hospital of Jilin UniversityCardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen UniversityInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow UniversityInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow UniversityDepartment of Cardiac Surgery, Fuwai HospitalKey Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, Guangzhou Medical UniversityInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow UniversityInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow Universityhttps://doi.org/10.1038/s41392-021-00520-8 |
| spellingShingle | Yanli Wang Wenping Xie Bin Liu Hui Huang Wei Luo Yu Zhang Xiangbin Pan Xi-Yong Yu Zhenya Shen Yangxin Li Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway Signal Transduction and Targeted Therapy |
| title | Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway |
| title_full | Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway |
| title_fullStr | Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway |
| title_full_unstemmed | Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway |
| title_short | Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway |
| title_sort | stem cell derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor rb1 mediated nlrp3 inflammasome pathway |
| url | https://doi.org/10.1038/s41392-021-00520-8 |
| work_keys_str_mv | AT yanliwang stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT wenpingxie stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT binliu stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT huihuang stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT weiluo stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT yuzhang stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT xiangbinpan stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT xiyongyu stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT zhenyashen stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway AT yangxinli stemcellderivedexosomesrepairischemicmuscleinjurybyinhibitingthetumorsuppressorrb1mediatednlrp3inflammasomepathway |