Molecular Structure of Cefuroxime Axetil Complexes with α-, β-, γ-, and 2-Hydroxypropyl-β-Cyclodextrins: Molecular Simulations and Raman Spectroscopic and Imaging Studies

Molecular Structure of Cefuroxime Axetil Complexes with α-, β-, γ-, and 2-Hydroxypropyl-β-Cyclodextrins: Molecular Simulations and Raman Spectroscopic and Imaging Studies

The formation of cefuroxime axetil+cyclodextrin (CA+CD) complexes increases the aqueous solubility of CA, improves its physico-chemical properties, and facilitates a biomembrane-mediated drug delivery process. In CD-based tablet formulations, it is crucial to investigate the molecular details of com...

Full description

Bibliographic Details
Main Authors: Barbara Gieroba, Grzegorz Kalisz, Anna Sroka-Bartnicka, Anita Płazińska, Wojciech Płaziński, Małgorzata Starek, Monika Dąbrowska
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
cefuroxime axetil
cyclodextrins
drug delivery
inclusion complexes
Raman spectroscopy
molecular dynamics
Online Access:https://www.mdpi.com/1422-0067/22/10/5238

Internet

https://www.mdpi.com/1422-0067/22/10/5238

Similar Items