Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
Prostate cancer is the second leading cause of cancer-related mortality in men. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of articles published from 1968 to 2007 assessing survival from prostate cancer was con...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2010-09-01
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Series: | American Journal of Men's Health |
Online Access: | https://doi.org/10.1177/1557988309353934 |
_version_ | 1818314667020255232 |
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author | Gayathri Sridhar MBBS, MPH, PhD Saba W. Masho MD, MPH Tilahun Adera MPH, PhD Viswanathan Ramakrishnan PhD John D. Roberts MD |
author_facet | Gayathri Sridhar MBBS, MPH, PhD Saba W. Masho MD, MPH Tilahun Adera MPH, PhD Viswanathan Ramakrishnan PhD John D. Roberts MD |
author_sort | Gayathri Sridhar MBBS, MPH, PhD |
collection | DOAJ |
description | Prostate cancer is the second leading cause of cancer-related mortality in men. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of articles published from 1968 to 2007 assessing survival from prostate cancer was conducted. Analysis of unadjusted studies reported that African American men have an increased risk of all-cause mortality (hazard ratio [HR] = 1.47, 95% confidence interval [CI] = 1.31-1.65, p < .001). However, examination of adjusted studies identified no difference (HR = 1.07, 95% CI = 0.94-1.22, p = .308). No statistically significant difference was observed in prostate cancer—specific survival in both analyses using unadjusted (HR = 1.11, 95% CI = 0.94-1.31, p = .209) and adjusted studies (HR = 1.15, 95% CI = 0.95-1.41, p = .157). This meta-analysis concludes that there are no racial differences in the overall and prostate cancer—specific survival between African American and White men. |
first_indexed | 2024-12-13T08:53:17Z |
format | Article |
id | doaj.art-11a193837e954e519607648c66f72110 |
institution | Directory Open Access Journal |
issn | 1557-9883 |
language | English |
last_indexed | 2024-12-13T08:53:17Z |
publishDate | 2010-09-01 |
publisher | SAGE Publishing |
record_format | Article |
series | American Journal of Men's Health |
spelling | doaj.art-11a193837e954e519607648c66f721102022-12-21T23:53:20ZengSAGE PublishingAmerican Journal of Men's Health1557-98832010-09-01410.1177/1557988309353934Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysisGayathri Sridhar MBBS, MPH, PhDSaba W. Masho MD, MPHTilahun Adera MPH, PhDViswanathan Ramakrishnan PhDJohn D. Roberts MDProstate cancer is the second leading cause of cancer-related mortality in men. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of articles published from 1968 to 2007 assessing survival from prostate cancer was conducted. Analysis of unadjusted studies reported that African American men have an increased risk of all-cause mortality (hazard ratio [HR] = 1.47, 95% confidence interval [CI] = 1.31-1.65, p < .001). However, examination of adjusted studies identified no difference (HR = 1.07, 95% CI = 0.94-1.22, p = .308). No statistically significant difference was observed in prostate cancer—specific survival in both analyses using unadjusted (HR = 1.11, 95% CI = 0.94-1.31, p = .209) and adjusted studies (HR = 1.15, 95% CI = 0.95-1.41, p = .157). This meta-analysis concludes that there are no racial differences in the overall and prostate cancer—specific survival between African American and White men.https://doi.org/10.1177/1557988309353934 |
spellingShingle | Gayathri Sridhar MBBS, MPH, PhD Saba W. Masho MD, MPH Tilahun Adera MPH, PhD Viswanathan Ramakrishnan PhD John D. Roberts MD Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis American Journal of Men's Health |
title | Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis |
title_full | Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis |
title_fullStr | Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis |
title_full_unstemmed | Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis |
title_short | Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis |
title_sort | do african american men have lower survival from prostate cancer compared with white men a meta analysis |
url | https://doi.org/10.1177/1557988309353934 |
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