Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis

Prostate cancer is the second leading cause of cancer-related mortality in men. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of articles published from 1968 to 2007 assessing survival from prostate cancer was con...

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Main Authors: Gayathri Sridhar MBBS, MPH, PhD, Saba W. Masho MD, MPH, Tilahun Adera MPH, PhD, Viswanathan Ramakrishnan PhD, John D. Roberts MD
Format: Article
Language:English
Published: SAGE Publishing 2010-09-01
Series:American Journal of Men's Health
Online Access:https://doi.org/10.1177/1557988309353934
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author Gayathri Sridhar MBBS, MPH, PhD
Saba W. Masho MD, MPH
Tilahun Adera MPH, PhD
Viswanathan Ramakrishnan PhD
John D. Roberts MD
author_facet Gayathri Sridhar MBBS, MPH, PhD
Saba W. Masho MD, MPH
Tilahun Adera MPH, PhD
Viswanathan Ramakrishnan PhD
John D. Roberts MD
author_sort Gayathri Sridhar MBBS, MPH, PhD
collection DOAJ
description Prostate cancer is the second leading cause of cancer-related mortality in men. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of articles published from 1968 to 2007 assessing survival from prostate cancer was conducted. Analysis of unadjusted studies reported that African American men have an increased risk of all-cause mortality (hazard ratio [HR] = 1.47, 95% confidence interval [CI] = 1.31-1.65, p < .001). However, examination of adjusted studies identified no difference (HR = 1.07, 95% CI = 0.94-1.22, p = .308). No statistically significant difference was observed in prostate cancer—specific survival in both analyses using unadjusted (HR = 1.11, 95% CI = 0.94-1.31, p = .209) and adjusted studies (HR = 1.15, 95% CI = 0.95-1.41, p = .157). This meta-analysis concludes that there are no racial differences in the overall and prostate cancer—specific survival between African American and White men.
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spelling doaj.art-11a193837e954e519607648c66f721102022-12-21T23:53:20ZengSAGE PublishingAmerican Journal of Men's Health1557-98832010-09-01410.1177/1557988309353934Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysisGayathri Sridhar MBBS, MPH, PhDSaba W. Masho MD, MPHTilahun Adera MPH, PhDViswanathan Ramakrishnan PhDJohn D. Roberts MDProstate cancer is the second leading cause of cancer-related mortality in men. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of articles published from 1968 to 2007 assessing survival from prostate cancer was conducted. Analysis of unadjusted studies reported that African American men have an increased risk of all-cause mortality (hazard ratio [HR] = 1.47, 95% confidence interval [CI] = 1.31-1.65, p < .001). However, examination of adjusted studies identified no difference (HR = 1.07, 95% CI = 0.94-1.22, p = .308). No statistically significant difference was observed in prostate cancer—specific survival in both analyses using unadjusted (HR = 1.11, 95% CI = 0.94-1.31, p = .209) and adjusted studies (HR = 1.15, 95% CI = 0.95-1.41, p = .157). This meta-analysis concludes that there are no racial differences in the overall and prostate cancer—specific survival between African American and White men.https://doi.org/10.1177/1557988309353934
spellingShingle Gayathri Sridhar MBBS, MPH, PhD
Saba W. Masho MD, MPH
Tilahun Adera MPH, PhD
Viswanathan Ramakrishnan PhD
John D. Roberts MD
Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
American Journal of Men's Health
title Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
title_full Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
title_fullStr Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
title_full_unstemmed Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
title_short Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
title_sort do african american men have lower survival from prostate cancer compared with white men a meta analysis
url https://doi.org/10.1177/1557988309353934
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