Drug Conjugates for Targeting Eph Receptors in Glioblastoma

Drug Conjugates for Targeting Eph Receptors in Glioblastoma

Glioblastoma (GBM) is a complex and heterogeneous tumor that warrants a comprehensive therapeutic approach for treatment. Tumor-associated antigens offer an opportunity to selectively target various components of the GBM microenvironment while sparing the normal cells within the central nervous syst...

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Bibliographic Details
Main Authors: Puja Sharma, Callie Roberts, Denise Herpai, Izabela D. Fokt, Waldemar Priebe, Waldemar Debinski
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceuticals
Subjects:
Eph receptors
multiple-receptor targeting
glioblastoma
ligand–drug conjugates
doxorubicin
Online Access:https://www.mdpi.com/1424-8247/13/4/77

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