Bone Mineral Density Loss in People With Epilepsy Taking Valproate as a Monotherapy: A Systematic Review and Meta-Analysis

Bone Mineral Density Loss in People With Epilepsy Taking Valproate as a Monotherapy: A Systematic Review and Meta-Analysis

Objective: Data on changes in bone mineral density (BMD) from valproate (VPA) therapy are ambiguous and conflicting. Thus, the aim of this study was to systematically review the existing data and carry out a meta-analysis to investigate the effect of VPA as a monotherapy on BMD in people with epilep...

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Bibliographic Details
Main Authors: Rui Zhong, Qingling Chen, Xinyue Zhang, Mengmeng Li, Jianmin Liang, Weihong Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
bone mineral density loss
epilepsy
valproate
meta-analysis
duration of VPA therapy
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01171/full

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