Murine fetal bone marrow does not support functional hematopoietic stem and progenitor cells until birth
Relatively little is known about the first hematopoietic stem and progenitor cells to arrive in the fetal bone marrow. Here they characterize the frequency, function, and molecular identity of fetal BM HSPCs and their bone marrow niche, and show that most BM HSPCs have little hematopoietic function...
Main Authors: | Trent D. Hall, Hyunjin Kim, Mahmoud Dabbah, Jacquelyn A. Myers, Jeremy Chase Crawford, Antonio Morales-Hernandez, Claire E. Caprio, Pramika Sriram, Emilia Kooienga, Marta Derecka, Esther A. Obeng, Paul G. Thomas, Shannon McKinney-Freeman |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33092-4 |
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