Murine fetal bone marrow does not support functional hematopoietic stem and progenitor cells until birth

Relatively little is known about the first hematopoietic stem and progenitor cells to arrive in the fetal bone marrow. Here they characterize the frequency, function, and molecular identity of fetal BM HSPCs and their bone marrow niche, and show that most BM HSPCs have little hematopoietic function...

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Bibliographic Details
Main Authors: Trent D. Hall, Hyunjin Kim, Mahmoud Dabbah, Jacquelyn A. Myers, Jeremy Chase Crawford, Antonio Morales-Hernandez, Claire E. Caprio, Pramika Sriram, Emilia Kooienga, Marta Derecka, Esther A. Obeng, Paul G. Thomas, Shannon McKinney-Freeman
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33092-4

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