Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
The histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environ...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2011-12-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800007&lng=en&tlng=en |
| _version_ | 1797757090107752448 |
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| author | Délia Cristina Figueira Aguiar Vera Lúcia de Souza Barros Washington Luiz Assunção Pereira Rosane do Socorro Pompeu de Loiola Gyselly Cássia Bastos de Matos João Valsecchi Tereza Cristina Oliveira Corvelo |
| author_facet | Délia Cristina Figueira Aguiar Vera Lúcia de Souza Barros Washington Luiz Assunção Pereira Rosane do Socorro Pompeu de Loiola Gyselly Cássia Bastos de Matos João Valsecchi Tereza Cristina Oliveira Corvelo |
| author_sort | Délia Cristina Figueira Aguiar |
| collection | DOAJ |
| description | The histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environment and potentially serve as ligands for pathogens or inhibitors of tissue connections. The objective of this paper was two-fold: (i) to determine the presence of Helicobacter sp. in the gastric mucosa of 16 captive and 24 free-living New World monkeys and (ii) to evaluate the presence of histopathological alterations related to bacterial infection and the associated expression of ABH antigens in the tissue. Stomach tissues from 13 species of monkey were assessed using haematoxylin-eosin and modified Gram staining (Hucker) methods. An immunohistochemical analysis of the tissue revealed the presence of infectious bacteria that were characteristic of the genus Helicobacter sp. The results demonstrate that various species of monkey might be naturally infected with the Helicobacter sp. and that there is an increased susceptibility to infection. This study serves as a comparative analysis of infection between human and non-human primates and indicates the presence of a new species of Helicobacter. |
| first_indexed | 2024-03-12T18:10:01Z |
| format | Article |
| id | doaj.art-11ad88af9e564cc5b2716f6695bcd1d2 |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:10:01Z |
| publishDate | 2011-12-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-11ad88af9e564cc5b2716f6695bcd1d22023-08-02T09:15:36ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80602011-12-01106893694110.1590/S0074-02762011000800007S0074-02762011000800007Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon regionDélia Cristina Figueira Aguiar0Vera Lúcia de Souza Barros1Washington Luiz Assunção Pereira2Rosane do Socorro Pompeu de Loiola3Gyselly Cássia Bastos de Matos4João Valsecchi5Tereza Cristina Oliveira Corvelo6Universidade Federal do ParáUniversidade Federal do ParáUniversidade Federal Rural da AmazôniaLaboratório Central do EstadoInstituto Evandro ChagasInstituto de Desenvolvimento Sustentável MamirauáUniversidade Federal do ParáThe histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environment and potentially serve as ligands for pathogens or inhibitors of tissue connections. The objective of this paper was two-fold: (i) to determine the presence of Helicobacter sp. in the gastric mucosa of 16 captive and 24 free-living New World monkeys and (ii) to evaluate the presence of histopathological alterations related to bacterial infection and the associated expression of ABH antigens in the tissue. Stomach tissues from 13 species of monkey were assessed using haematoxylin-eosin and modified Gram staining (Hucker) methods. An immunohistochemical analysis of the tissue revealed the presence of infectious bacteria that were characteristic of the genus Helicobacter sp. The results demonstrate that various species of monkey might be naturally infected with the Helicobacter sp. and that there is an increased susceptibility to infection. This study serves as a comparative analysis of infection between human and non-human primates and indicates the presence of a new species of Helicobacter.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800007&lng=en&tlng=enNew World primatesHelicobacter sp.- ABO blood group systemimmunohistochemistry |
| spellingShingle | Délia Cristina Figueira Aguiar Vera Lúcia de Souza Barros Washington Luiz Assunção Pereira Rosane do Socorro Pompeu de Loiola Gyselly Cássia Bastos de Matos João Valsecchi Tereza Cristina Oliveira Corvelo Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region Memorias do Instituto Oswaldo Cruz New World primates Helicobacter sp. - ABO blood group system immunohistochemistry |
| title | Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region |
| title_full | Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region |
| title_fullStr | Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region |
| title_full_unstemmed | Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region |
| title_short | Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region |
| title_sort | immunodetection of helicobacter sp and the associated expression of abo blood group antigens in the gastric mucosa of captive and free living new world primates in the amazon region |
| topic | New World primates Helicobacter sp. - ABO blood group system immunohistochemistry |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800007&lng=en&tlng=en |
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