Single-cell glycomics analysis by CyTOF-Lec reveals glycan features defining cells differentially susceptible to HIV

Single-cell glycomics analysis by CyTOF-Lec reveals glycan features defining cells differentially susceptible to HIV

High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously characterize many protein and glycan features of human immune cells at th...

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Bibliographic Details
Main Authors: Tongcui Ma, Matthew McGregor, Leila Giron, Guorui Xie, Ashley F George, Mohamed Abdel-Mohsen, Nadia R Roan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
CyTOF
glycans
HIV
T cells
lectins
sialic acid
Online Access:https://elifesciences.org/articles/78870

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