Skin regeneration is accelerated by a lower dose of multipotent mesenchymal stromal/stem cells—a paradigm change

Skin regeneration is accelerated by a lower dose of multipotent mesenchymal stromal/stem cells—a paradigm change

Abstract Background Multipotent mesenchymal stromal/stem cell (MSC) therapy is under investigation in promising (pre-)clinical trials for wound healing, which is crucial for survival; however, the optimal cell dosage remains unknown. The aim was to investigate the efficacy of different low-to-high M...

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Bibliographic Details
Main Authors: Gertraud Eylert, Reinhard Dolp, Alexandra Parousis, Richard Cheng, Christopher Auger, Magdalena Holter, Ingrid Lang-Olip, Viola Reiner, Lars-Peter Kamolz, Marc G. Jeschke
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Skin regeneration
Multipotent mesenchymal stromal/stem cells
Wound healing
Cell therapy
Tissue engineering
Integra
Online Access:https://doi.org/10.1186/s13287-020-02131-6

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