Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis
Abstract Background This meta-analysis was designed to investigate the long-term efficacy and safety between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) in treating cervical disc degenerative diseases (CDDDs). Methods Literature search was performed on Pubmed,...
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| Format: | Article |
| Language: | English |
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BMC
2020-04-01
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| Series: | BMC Neurology |
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| Online Access: | http://link.springer.com/article/10.1186/s12883-020-01717-0 |
| _version_ | 1818528080966189056 |
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| author | Yijian Zhang Nanning Lv Fan He Bin Pi Hao Liu Angela Carley Chen Huilin Yang Mingming Liu Xuesong Zhu |
| author_facet | Yijian Zhang Nanning Lv Fan He Bin Pi Hao Liu Angela Carley Chen Huilin Yang Mingming Liu Xuesong Zhu |
| author_sort | Yijian Zhang |
| collection | DOAJ |
| description | Abstract Background This meta-analysis was designed to investigate the long-term efficacy and safety between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) in treating cervical disc degenerative diseases (CDDDs). Methods Literature search was performed on Pubmed, Embase, Cochrane Library, and Web of Science before Jan 2019. Surgical details, clinical outcomes, range of motion (ROM), complications, and reoperation rates between CDA and ACDF groups were compared and analyzed. A fixed- or random-effects model was applied based on different heterogeneity. STATA (Version 11.0) software was used to perform data analysis. Results A total of 13 randomized controlled trial studies with more than 60 months of follow-up (mean 83.1 months) were enrolled in this meta-analysis. Pool results indicated that the CDA group exhibited significantly better outcomes in clinical scores (odds ratio [OR] = 1.54, 95% confidence interval [CI]: 1.15–2.08, p = 0.004) and preservation of ROM (mean difference = 1.77, 95% CI: 1.60–1.95, p < 0.001) than the ACDF group. Meanwhile, the incidence of adjacent segment disease (ASD) (OR = 0.51, 95% CI: 0.35–0.76, p = 0.001) and occurrence of reoperation (OR = 0.41, 95% CI: 0.25–0.69, p = 0.001) were lower in the CDA group than in the ACDF group. Conclusions At long-term follow-up, CDA showed better efficacy in terms of clinical outcomes, ROM, ASD, and reoperation than ACDF for treating CDDDs. However, our results require further validation in large-sample and high-quality studies. |
| first_indexed | 2024-12-11T06:44:59Z |
| format | Article |
| id | doaj.art-11b7f13cdfa94dfe8ff184f5a72e7792 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-12-11T06:44:59Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-11b7f13cdfa94dfe8ff184f5a72e77922022-12-22T01:17:06ZengBMCBMC Neurology1471-23772020-04-0120111210.1186/s12883-020-01717-0Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysisYijian Zhang0Nanning Lv1Fan He2Bin Pi3Hao Liu4Angela Carley Chen5Huilin Yang6Mingming Liu7Xuesong Zhu8Department of Orthopedics, The First Affiliated Hospital of Soochow UniversityDepartment of Orthopedic Surgery, The Second People’s Hospital of LianyungangDepartment of Orthopedics, The First Affiliated Hospital of Soochow UniversityDepartment of Orthopedics, The First Affiliated Hospital of Soochow UniversityDepartment of Orthopedics, The First Affiliated Hospital of Soochow UniversitySchool of Public Health and Health Systems, University of WaterlooDepartment of Orthopedics, The First Affiliated Hospital of Soochow UniversityDepartment of Orthopedic Surgery, The Second People’s Hospital of LianyungangDepartment of Orthopedics, The First Affiliated Hospital of Soochow UniversityAbstract Background This meta-analysis was designed to investigate the long-term efficacy and safety between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) in treating cervical disc degenerative diseases (CDDDs). Methods Literature search was performed on Pubmed, Embase, Cochrane Library, and Web of Science before Jan 2019. Surgical details, clinical outcomes, range of motion (ROM), complications, and reoperation rates between CDA and ACDF groups were compared and analyzed. A fixed- or random-effects model was applied based on different heterogeneity. STATA (Version 11.0) software was used to perform data analysis. Results A total of 13 randomized controlled trial studies with more than 60 months of follow-up (mean 83.1 months) were enrolled in this meta-analysis. Pool results indicated that the CDA group exhibited significantly better outcomes in clinical scores (odds ratio [OR] = 1.54, 95% confidence interval [CI]: 1.15–2.08, p = 0.004) and preservation of ROM (mean difference = 1.77, 95% CI: 1.60–1.95, p < 0.001) than the ACDF group. Meanwhile, the incidence of adjacent segment disease (ASD) (OR = 0.51, 95% CI: 0.35–0.76, p = 0.001) and occurrence of reoperation (OR = 0.41, 95% CI: 0.25–0.69, p = 0.001) were lower in the CDA group than in the ACDF group. Conclusions At long-term follow-up, CDA showed better efficacy in terms of clinical outcomes, ROM, ASD, and reoperation than ACDF for treating CDDDs. However, our results require further validation in large-sample and high-quality studies.http://link.springer.com/article/10.1186/s12883-020-01717-0Cervical disc arthroplastyAnterior cervical discectomy and fusionCervical degenerative disc diseasesLong-term follow-up |
| spellingShingle | Yijian Zhang Nanning Lv Fan He Bin Pi Hao Liu Angela Carley Chen Huilin Yang Mingming Liu Xuesong Zhu Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis BMC Neurology Cervical disc arthroplasty Anterior cervical discectomy and fusion Cervical degenerative disc diseases Long-term follow-up |
| title | Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis |
| title_full | Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis |
| title_fullStr | Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis |
| title_full_unstemmed | Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis |
| title_short | Comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow-up: a systematic review and meta-analysis |
| title_sort | comparison of cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical disc degenerative diseases on the basis of more than 60 months of follow up a systematic review and meta analysis |
| topic | Cervical disc arthroplasty Anterior cervical discectomy and fusion Cervical degenerative disc diseases Long-term follow-up |
| url | http://link.springer.com/article/10.1186/s12883-020-01717-0 |
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