Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty
Abstract Background The purpose of this meta-analysis was to assess the efficacy of intrathecal morphine (ITM) analgesia and local infiltration analgesia (LIA) for pain control in total joint arthroplasty (TJA). Methods Embase, PubMed, the Cochrane Library, and Web of Science were systematically sea...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | http://link.springer.com/article/10.1186/s13018-020-01627-4 |
| _version_ | 1798040244647362560 |
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| author | Ai-Lan Cai Sheng-Jie Liu Bin Wu Geng Liu |
| author_facet | Ai-Lan Cai Sheng-Jie Liu Bin Wu Geng Liu |
| author_sort | Ai-Lan Cai |
| collection | DOAJ |
| description | Abstract Background The purpose of this meta-analysis was to assess the efficacy of intrathecal morphine (ITM) analgesia and local infiltration analgesia (LIA) for pain control in total joint arthroplasty (TJA). Methods Embase, PubMed, the Cochrane Library, and Web of Science were systematically searched for randomized controlled trials (RCTs). All RCTs were comparing intrathecal analgesia and local infiltration analgesia in TJA. Primary outcomes were the visual analog scale (VAS) score with rest or mobilization up to 72 h. Secondary outcomes were the total morphine consumption, length of hospital stay, and morphine-related complications. Results Compared with the intrathecal analgesia group, the LIA group was associated with a reduction in VAS score with rest up to 72 h. Moreover, LIA was associated with a decrease in VAS score with mobilization at 6 h, 12 h, 48 h, and 72 h. Moreover, LIA significantly reduced total morphine consumption (weighted mean difference (WMD) = − 15.37, 95% CI − 22.64 to − 8.83, P = 0.000), length of hospital stay (WMD = − 1.39, 95% CI − 1.67 to − 1.11, P = 0.000), and morphine-related complications (nausea and pruritus). Conclusions Local infiltration provided superior analgesia and morphine-sparing effects within the first 72 h compared with ITM following TJA. |
| first_indexed | 2024-04-11T22:04:47Z |
| format | Article |
| id | doaj.art-11b823d5dffd4a0f8f098bafaba37098 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-11T22:04:47Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-11b823d5dffd4a0f8f098bafaba370982022-12-22T04:00:45ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2020-03-0115111010.1186/s13018-020-01627-4Intrathecal versus local infiltration analgesia for pain control in total joint arthroplastyAi-Lan Cai0Sheng-Jie Liu1Bin Wu2Geng Liu3Anesthesiology Department, Liaocheng People’s HospitalAnesthesiology Department, Liaocheng People’s HospitalAnesthesiology Department, Liaocheng People’s HospitalAnesthesiology Department, Liaocheng People’s HospitalAbstract Background The purpose of this meta-analysis was to assess the efficacy of intrathecal morphine (ITM) analgesia and local infiltration analgesia (LIA) for pain control in total joint arthroplasty (TJA). Methods Embase, PubMed, the Cochrane Library, and Web of Science were systematically searched for randomized controlled trials (RCTs). All RCTs were comparing intrathecal analgesia and local infiltration analgesia in TJA. Primary outcomes were the visual analog scale (VAS) score with rest or mobilization up to 72 h. Secondary outcomes were the total morphine consumption, length of hospital stay, and morphine-related complications. Results Compared with the intrathecal analgesia group, the LIA group was associated with a reduction in VAS score with rest up to 72 h. Moreover, LIA was associated with a decrease in VAS score with mobilization at 6 h, 12 h, 48 h, and 72 h. Moreover, LIA significantly reduced total morphine consumption (weighted mean difference (WMD) = − 15.37, 95% CI − 22.64 to − 8.83, P = 0.000), length of hospital stay (WMD = − 1.39, 95% CI − 1.67 to − 1.11, P = 0.000), and morphine-related complications (nausea and pruritus). Conclusions Local infiltration provided superior analgesia and morphine-sparing effects within the first 72 h compared with ITM following TJA.http://link.springer.com/article/10.1186/s13018-020-01627-4Intrathecal analgesiaLocal infiltration analgesiaTotal joint arthroplastyMeta-analysis |
| spellingShingle | Ai-Lan Cai Sheng-Jie Liu Bin Wu Geng Liu Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty Journal of Orthopaedic Surgery and Research Intrathecal analgesia Local infiltration analgesia Total joint arthroplasty Meta-analysis |
| title | Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty |
| title_full | Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty |
| title_fullStr | Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty |
| title_full_unstemmed | Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty |
| title_short | Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty |
| title_sort | intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty |
| topic | Intrathecal analgesia Local infiltration analgesia Total joint arthroplasty Meta-analysis |
| url | http://link.springer.com/article/10.1186/s13018-020-01627-4 |
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