Development of a COX-2-Selective Fluorescent Probe for the Observation of Early Intervertebral Disc Degeneration

Development of a COX-2-Selective Fluorescent Probe for the Observation of Early Intervertebral Disc Degeneration

Cyclooxygenase-2 (COX-2) is a biomolecule known to be overexpressed in inflammation. Therefore, it has been considered a diagnostically useful marker in numerous studies. In this study, we attempted to assess the correlation between COX-2 expression and the severity of intervertebral disc (IVD) dege...

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Bibliographic Details
Main Authors: Cheol Ho Heo, Eun Ji Roh, Jaehee Kim, Hyemin Choi, Ho Yeon Jang, Giseong Lee, Chang Su Lim, Inbo Han
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Functional Biomaterials
Subjects:
intervertebral disc
fluorescent probe
cyclooxygenase-2 (COX-2)
diagnosis of intervertebral disc (IVD) degeneration
bioimaging
spinal disease
Online Access:https://www.mdpi.com/2079-4983/14/4/192

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