Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration
Abstract Neurodegenerative diseases are accompanied by dynamic changes in gene expression, including the upregulation of hallmark stress-responsive genes. While the transcriptional pathways that impart adaptive and maladaptive gene expression signatures have been the focus of intense study, the role...
Main Authors: | Ivana Herrera, José Alex Lourenço Fernandes, Khatereh Shir-Mohammadi, Jasmine Levesque, Pierre Mattar |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-10-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-06224-x |
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