Paracrine Activation of the Wnt/β-Catenin Pathway by Bone Marrow Stem Cell Attenuates Cisplatin-Induced Kidney Injury

Paracrine Activation of the Wnt/β-Catenin Pathway by Bone Marrow Stem Cell Attenuates Cisplatin-Induced Kidney Injury

Background/Aims: Cisplatin-induced acute kidney injury (AKI) involves damage to tubular cells via excess reactive oxygen species (ROS) generation. Stem cell-based therapies have shown great promise in AKI treatment. In this study, we aimed to assess the protective effect and mechanism of bone marrow...

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Bibliographic Details
Main Authors: Xiaoyan Jiao, Jieru Cai, Xiaofang Yu, Xiaoqiang Ding
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Acute kidney injury
Cisplatin-induced kidney injury
Bone marrow mesenchymal stem cell
Wnt/β-catenin pathway
Paracrine effect
Online Access:https://www.karger.com/Article/FullText/485904

Internet

https://www.karger.com/Article/FullText/485904

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