Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone
Meningiomas in bone are rarely subjected to fine-needle aspiration diagnosis, and those arising in the skull bone with a cystic presentation are rare. A 24-year-old woman presented with subdural hemorrhage, and subsequent radiology depicted an osteolytic mass-like lesion in the sphenoid bone. Intrao...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Pathologists & the Korean Society for Cytopathology
2020-11-01
|
| Series: | Journal of Pathology and Translational Medicine |
| Subjects: | |
| Online Access: | http://www.jpatholtm.org/upload/pdf/jptm-2020-05-21.pdf |
| _version_ | 1828810064530505728 |
|---|---|
| author | Na Rae Kim Gie-Taek Yie |
| author_facet | Na Rae Kim Gie-Taek Yie |
| author_sort | Na Rae Kim |
| collection | DOAJ |
| description | Meningiomas in bone are rarely subjected to fine-needle aspiration diagnosis, and those arising in the skull bone with a cystic presentation are rare. A 24-year-old woman presented with subdural hemorrhage, and subsequent radiology depicted an osteolytic mass-like lesion in the sphenoid bone. Intraoperatively, a solid and cystic hemorrhagic lesion mimicking an aneurysmal bone cyst was observed in the sphenoid bone with dural tearing. Frozen cytology showed singly scattered or epithelioid clusters of round to elongated cells intermixed with many neutrophils. Tumor cells had bland-looking round nuclei with rare prominent nucleoli and nuclear inclusions and eosinophilic granular to globoid cytoplasm in capillary-rich fragments. Histology revealed intraosseous meningothelial and microcystic meningioma (World Health Organization grade 1) in right lesser wing of the sphenoid bone. Considering its unusual location and cytologic findings, differential diagnoses included chordoma, chondroma, chondrosarcoma, and aneurysmal bone cyst. The present case posed a diagnostic challenge due to possible confusion with these entities. |
| first_indexed | 2024-12-12T09:06:10Z |
| format | Article |
| id | doaj.art-11c532f9aa5a4efd951f024dad2c88e6 |
| institution | Directory Open Access Journal |
| issn | 2383-7837 2383-7845 |
| language | English |
| last_indexed | 2024-12-12T09:06:10Z |
| publishDate | 2020-11-01 |
| publisher | Korean Society of Pathologists & the Korean Society for Cytopathology |
| record_format | Article |
| series | Journal of Pathology and Translational Medicine |
| spelling | doaj.art-11c532f9aa5a4efd951f024dad2c88e62022-12-22T00:29:40ZengKorean Society of Pathologists & the Korean Society for CytopathologyJournal of Pathology and Translational Medicine2383-78372383-78452020-11-0154650851210.4132/jptm.2020.05.2116919Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid boneNa Rae Kim0Gie-Taek Yie1 Department of Pathology, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Neurosurgery, Gil Medical Center, Gachon University College of Medicine, Incheon, KoreaMeningiomas in bone are rarely subjected to fine-needle aspiration diagnosis, and those arising in the skull bone with a cystic presentation are rare. A 24-year-old woman presented with subdural hemorrhage, and subsequent radiology depicted an osteolytic mass-like lesion in the sphenoid bone. Intraoperatively, a solid and cystic hemorrhagic lesion mimicking an aneurysmal bone cyst was observed in the sphenoid bone with dural tearing. Frozen cytology showed singly scattered or epithelioid clusters of round to elongated cells intermixed with many neutrophils. Tumor cells had bland-looking round nuclei with rare prominent nucleoli and nuclear inclusions and eosinophilic granular to globoid cytoplasm in capillary-rich fragments. Histology revealed intraosseous meningothelial and microcystic meningioma (World Health Organization grade 1) in right lesser wing of the sphenoid bone. Considering its unusual location and cytologic findings, differential diagnoses included chordoma, chondroma, chondrosarcoma, and aneurysmal bone cyst. The present case posed a diagnostic challenge due to possible confusion with these entities.http://www.jpatholtm.org/upload/pdf/jptm-2020-05-21.pdfmeningiomaskullsphenoid boneosteolysisbone cysts, aneurysmal |
| spellingShingle | Na Rae Kim Gie-Taek Yie Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone Journal of Pathology and Translational Medicine meningioma skull sphenoid bone osteolysis bone cysts, aneurysmal |
| title | Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone |
| title_full | Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone |
| title_fullStr | Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone |
| title_full_unstemmed | Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone |
| title_short | Intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone |
| title_sort | intraoperative frozen cytology of intraosseous cystic meningioma in the sphenoid bone |
| topic | meningioma skull sphenoid bone osteolysis bone cysts, aneurysmal |
| url | http://www.jpatholtm.org/upload/pdf/jptm-2020-05-21.pdf |
| work_keys_str_mv | AT naraekim intraoperativefrozencytologyofintraosseouscysticmeningiomainthesphenoidbone AT gietaekyie intraoperativefrozencytologyofintraosseouscysticmeningiomainthesphenoidbone |