Granular Cell Tumor of the Ascending Colon
Granular cell tumor (GCT) was first described by Abrikossoff in 1926. It is a mostly benign tumor with rare malignant transformation. It is defined as a soft tissue neoplasm with abundant eosinophilic cytoplasm. The mean age of diagnosis for GCT is around 45 years. It is rare for GCT to be found in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2023-02-01
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| Series: | Case Reports in Gastroenterology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/529170 |
| _version_ | 1797869525010481152 |
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| author | Samyak Dhruv Kuldeepsinh P. Atodaria Dhineshreddy Gurala Talal El Imad Jeffrey Abergel |
| author_facet | Samyak Dhruv Kuldeepsinh P. Atodaria Dhineshreddy Gurala Talal El Imad Jeffrey Abergel |
| author_sort | Samyak Dhruv |
| collection | DOAJ |
| description | Granular cell tumor (GCT) was first described by Abrikossoff in 1926. It is a mostly benign tumor with rare malignant transformation. It is defined as a soft tissue neoplasm with abundant eosinophilic cytoplasm. The mean age of diagnosis for GCT is around 45 years. It is rare for GCT to be found in the gastrointestinal (GI) tract. Within the subset of GI tract, the colon is an extremely rare site for it to be found. Franburg-Smith histopathology criteria are used to differentiate a benign from a malignant GCT. The malignant form is aggressive with high recurrence rates after resection. Histopathology and immunohistochemical stains are used to make a definitive diagnosis. Herein, we present a rare case of an ascending colon polyp that was resected and found to be a benign GCT. |
| first_indexed | 2024-04-10T00:12:52Z |
| format | Article |
| id | doaj.art-11c6d07ca4594ed9a17e135aa2f9c470 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-04-10T00:12:52Z |
| publishDate | 2023-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-11c6d07ca4594ed9a17e135aa2f9c4702023-03-16T06:57:28ZengKarger PublishersCase Reports in Gastroenterology1662-06312023-02-0117110410810.1159/000529170529170Granular Cell Tumor of the Ascending ColonSamyak Dhruv0Kuldeepsinh P. Atodaria1https://orcid.org/0000-0002-1786-920XDhineshreddy Gurala2Talal El Imad3Jeffrey Abergel4Hospitalist doctor of Internal Medicine at MedStar St. Mary’s Hospital, Leonardtown, MD, USAInternal Medicine Resident at Abington Health, Abington, PA, USAGastroenterology Fellow at Staten Island University Hospital, Staten Island, New York, NY, USAGastroenterologist with Advantage Care Physicians, New York, NY, USAGastroenterologist at New York, Presbyterian Medical Group Hudson Valley, New York, NY, USAGranular cell tumor (GCT) was first described by Abrikossoff in 1926. It is a mostly benign tumor with rare malignant transformation. It is defined as a soft tissue neoplasm with abundant eosinophilic cytoplasm. The mean age of diagnosis for GCT is around 45 years. It is rare for GCT to be found in the gastrointestinal (GI) tract. Within the subset of GI tract, the colon is an extremely rare site for it to be found. Franburg-Smith histopathology criteria are used to differentiate a benign from a malignant GCT. The malignant form is aggressive with high recurrence rates after resection. Histopathology and immunohistochemical stains are used to make a definitive diagnosis. Herein, we present a rare case of an ascending colon polyp that was resected and found to be a benign GCT.https://www.karger.com/Article/FullText/529170colonoscopygranular cell tumorcolon polyppedunculated polyp |
| spellingShingle | Samyak Dhruv Kuldeepsinh P. Atodaria Dhineshreddy Gurala Talal El Imad Jeffrey Abergel Granular Cell Tumor of the Ascending Colon Case Reports in Gastroenterology colonoscopy granular cell tumor colon polyp pedunculated polyp |
| title | Granular Cell Tumor of the Ascending Colon |
| title_full | Granular Cell Tumor of the Ascending Colon |
| title_fullStr | Granular Cell Tumor of the Ascending Colon |
| title_full_unstemmed | Granular Cell Tumor of the Ascending Colon |
| title_short | Granular Cell Tumor of the Ascending Colon |
| title_sort | granular cell tumor of the ascending colon |
| topic | colonoscopy granular cell tumor colon polyp pedunculated polyp |
| url | https://www.karger.com/Article/FullText/529170 |
| work_keys_str_mv | AT samyakdhruv granularcelltumoroftheascendingcolon AT kuldeepsinhpatodaria granularcelltumoroftheascendingcolon AT dhineshreddygurala granularcelltumoroftheascendingcolon AT talalelimad granularcelltumoroftheascendingcolon AT jeffreyabergel granularcelltumoroftheascendingcolon |