The Binding of Monoclonal and Polyclonal Anti-Z-DNA Antibodies to DNA of Various Species Origin

The Binding of Monoclonal and Polyclonal Anti-Z-DNA Antibodies to DNA of Various Species Origin

DNA is a polymeric macromolecule that can display a variety of backbone conformations. While the classical B-DNA is a right-handed double helix, Z-DNA is a left-handed helix with a zig-zag orientation. The Z conformation depends upon the base sequence, base modification and supercoiling and is consi...

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Bibliographic Details
Main Authors: Diane M. Spencer, Angel Garza Reyna, David S. Pisetsky
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
DNA
Z-DNA
B-DNA
immunoassay
anti-DNA antibodies
conformation
Online Access:https://www.mdpi.com/1422-0067/22/16/8931

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