Rapid sex-specific adaptation to high temperature in Drosophila
The pervasive occurrence of sexual dimorphism demonstrates different adaptive strategies of males and females. While different reproductive strategies of the two sexes are well-characterized, very little is known about differential functional requirements of males and females in their natural habita...
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2020-02-01
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| Series: | eLife |
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| Online Access: | https://elifesciences.org/articles/53237 |
| _version_ | 1811202921417670656 |
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| author | Sheng-Kai Hsu Ana Marija Jakšić Viola Nolte Manolis Lirakis Robert Kofler Neda Barghi Elisabetta Versace Christian Schlötterer |
| author_facet | Sheng-Kai Hsu Ana Marija Jakšić Viola Nolte Manolis Lirakis Robert Kofler Neda Barghi Elisabetta Versace Christian Schlötterer |
| author_sort | Sheng-Kai Hsu |
| collection | DOAJ |
| description | The pervasive occurrence of sexual dimorphism demonstrates different adaptive strategies of males and females. While different reproductive strategies of the two sexes are well-characterized, very little is known about differential functional requirements of males and females in their natural habitats. Here, we study the impact environmental change on the selection response in both sexes. Exposing replicated Drosophila populations to a novel temperature regime, we demonstrate sex-specific changes in gene expression, metabolic and behavioral phenotypes in less than 100 generations. This indicates not only different functional requirements of both sexes in the new environment but also rapid sex-specific adaptation. Supported by computer simulations we propose that altered sex-biased gene regulation from standing genetic variation, rather than new mutations, is the driver of rapid sex-specific adaptation. Our discovery of environmentally driven divergent functional requirements of males and females has important implications-possibly even for gender aware medical treatments. |
| first_indexed | 2024-04-12T02:45:58Z |
| format | Article |
| id | doaj.art-11d606fd93044915a50af9a61f71ba83 |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T02:45:58Z |
| publishDate | 2020-02-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-11d606fd93044915a50af9a61f71ba832022-12-22T03:51:09ZengeLife Sciences Publications LtdeLife2050-084X2020-02-01910.7554/eLife.53237Rapid sex-specific adaptation to high temperature in DrosophilaSheng-Kai Hsu0https://orcid.org/0000-0002-6942-7163Ana Marija Jakšić1https://orcid.org/0000-0002-2293-255XViola Nolte2Manolis Lirakis3Robert Kofler4Neda Barghi5https://orcid.org/0000-0003-3700-0971Elisabetta Versace6https://orcid.org/0000-0003-4578-1851Christian Schlötterer7https://orcid.org/0000-0003-4710-6526Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria; Vienna Graduate School of Population Genetics, Vetmeduni Vienna, Vienna, AustriaInstitut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria; Vienna Graduate School of Population Genetics, Vetmeduni Vienna, Vienna, AustriaInstitut für Populationsgenetik, Vetmeduni Vienna, Vienna, AustriaInstitut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria; Vienna Graduate School of Population Genetics, Vetmeduni Vienna, Vienna, AustriaInstitut für Populationsgenetik, Vetmeduni Vienna, Vienna, AustriaInstitut für Populationsgenetik, Vetmeduni Vienna, Vienna, AustriaDepartment of Biological and Experimental Psychology, Queen Mary University of London, London, United KingdomInstitut für Populationsgenetik, Vetmeduni Vienna, Vienna, AustriaThe pervasive occurrence of sexual dimorphism demonstrates different adaptive strategies of males and females. While different reproductive strategies of the two sexes are well-characterized, very little is known about differential functional requirements of males and females in their natural habitats. Here, we study the impact environmental change on the selection response in both sexes. Exposing replicated Drosophila populations to a novel temperature regime, we demonstrate sex-specific changes in gene expression, metabolic and behavioral phenotypes in less than 100 generations. This indicates not only different functional requirements of both sexes in the new environment but also rapid sex-specific adaptation. Supported by computer simulations we propose that altered sex-biased gene regulation from standing genetic variation, rather than new mutations, is the driver of rapid sex-specific adaptation. Our discovery of environmentally driven divergent functional requirements of males and females has important implications-possibly even for gender aware medical treatments.https://elifesciences.org/articles/53237sexual dimorphismsex-specific adaptationexperimental evolutionDrosophila simulans |
| spellingShingle | Sheng-Kai Hsu Ana Marija Jakšić Viola Nolte Manolis Lirakis Robert Kofler Neda Barghi Elisabetta Versace Christian Schlötterer Rapid sex-specific adaptation to high temperature in Drosophila eLife sexual dimorphism sex-specific adaptation experimental evolution Drosophila simulans |
| title | Rapid sex-specific adaptation to high temperature in Drosophila |
| title_full | Rapid sex-specific adaptation to high temperature in Drosophila |
| title_fullStr | Rapid sex-specific adaptation to high temperature in Drosophila |
| title_full_unstemmed | Rapid sex-specific adaptation to high temperature in Drosophila |
| title_short | Rapid sex-specific adaptation to high temperature in Drosophila |
| title_sort | rapid sex specific adaptation to high temperature in drosophila |
| topic | sexual dimorphism sex-specific adaptation experimental evolution Drosophila simulans |
| url | https://elifesciences.org/articles/53237 |
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