Modeling the stem cell hypothesis: Investigating the effects of cancer stem cells and TGF−β on tumor growth
We propose a mathematical model to describe the interaction of cancer stem cells, tumor cells, and the immune system in order to better understand tumor growth in the presence of cancer stem cells. We consider the system in two scenarios: with no-treatment and with a chemotherapy treatment regimen....
Main Authors: | Samantha L Elliott, Emek Kose, Allison L Lewis, Anna E Steinfeld, Elizabeth A Zollinger |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2019-08-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/10.3934/mbe.2019360?viewType=HTML |
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