YAP-mediated mechanotransduction in urinary bladder remodeling: Based on RNA-seq and CUT&Tag

YAP-mediated mechanotransduction in urinary bladder remodeling: Based on RNA-seq and CUT&Tag

Yes-associated protein (YAP) is an important transcriptional coactivator binding to transcriptional factors that engage in many downstream gene transcription. Partial bladder outlet obstruction (pBOO) causes a massive burden to patients and finally leads to bladder fibrosis. Several cell types engag...

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Bibliographic Details
Main Authors: Xingpeng Di, Liyuan Xiang, Zhongyu Jian
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
RNA-seq
CUT&Tag
YAP
bladder remodeling
mechanotransduction
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1106927/full

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