ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER
Given study was aimed to research a role of kinetic performance of PSA in selection of the patients for conduction ¹¹C-choline PET/CT in order to reveal local recurrences in patient with prostate cancer after radiation therapy (RT) and radical prostatectomy (RP). The study included 185 patients with...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Pavlov First Saint Petersburg State Medical University
2015-12-01
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| Series: | Вестник хирургии имени И.И. Грекова |
| Subjects: | |
| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/138 |
| _version_ | 1797877778804113408 |
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| author | M. A. Rybalov I. Ya. De Iong A. I. Breusma S. Kh. Al’-Shukri S. Yu. Borovets |
| author_facet | M. A. Rybalov I. Ya. De Iong A. I. Breusma S. Kh. Al’-Shukri S. Yu. Borovets |
| author_sort | M. A. Rybalov |
| collection | DOAJ |
| description | Given study was aimed to research a role of kinetic performance of PSA in selection of the patients for conduction ¹¹C-choline PET/CT in order to reveal local recurrences in patient with prostate cancer after radiation therapy (RT) and radical prostatectomy (RP). The study included 185 patients with histologically distinctive prostate cancer and biochemical signs of tumor recurrence after RP (61 patients) or RT (124 patients). All the patients were examined using ¹¹C-choline PET/ CT in order to detect local relapses. Calculation of growth rate of the PSA level and PSA doubling time were made. According to results of ¹¹C-choline PET/CT, recurrences of prostate cancer were detected in 124 out of 185 (65%). There were 22 patients out of 61 (36%) after RP and there were 102 patients out of 124 (82%) after RT. It was stated a correlation between PSA rates, growth rate of PSA level and presence or absence of relapse according to PET/CT results. PSA level and growth rate of PSA were indicated as the most significant predictive signs, which could influence on the selection of the patients for conduction of ¹¹C-choline PET/CT in relation to detection of local recurrence after RT and RP. |
| first_indexed | 2024-04-10T02:23:26Z |
| format | Article |
| id | doaj.art-11dc27c3030e463a936aa99bb711b998 |
| institution | Directory Open Access Journal |
| issn | 0042-4625 |
| language | Russian |
| last_indexed | 2024-04-10T02:23:26Z |
| publishDate | 2015-12-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj.art-11dc27c3030e463a936aa99bb711b9982023-03-13T08:09:09ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252015-12-011746252810.24884/0042-4625-2015-174-6-25-28137ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCERM. A. Rybalov0I. Ya. De Iong1A. I. Breusma2S. Kh. Al’-Shukri3S. Yu. Borovets4Medical centre of Groningen University; I. P.Pavlov Saint-Petersburg First State Medical UniversityMedical centre of Groningen UniversityMedical centre of Groningen UniversityI. P.Pavlov Saint-Petersburg First State Medical UniversityI. P.Pavlov Saint-Petersburg First State Medical UniversityGiven study was aimed to research a role of kinetic performance of PSA in selection of the patients for conduction ¹¹C-choline PET/CT in order to reveal local recurrences in patient with prostate cancer after radiation therapy (RT) and radical prostatectomy (RP). The study included 185 patients with histologically distinctive prostate cancer and biochemical signs of tumor recurrence after RP (61 patients) or RT (124 patients). All the patients were examined using ¹¹C-choline PET/ CT in order to detect local relapses. Calculation of growth rate of the PSA level and PSA doubling time were made. According to results of ¹¹C-choline PET/CT, recurrences of prostate cancer were detected in 124 out of 185 (65%). There were 22 patients out of 61 (36%) after RP and there were 102 patients out of 124 (82%) after RT. It was stated a correlation between PSA rates, growth rate of PSA level and presence or absence of relapse according to PET/CT results. PSA level and growth rate of PSA were indicated as the most significant predictive signs, which could influence on the selection of the patients for conduction of ¹¹C-choline PET/CT in relation to detection of local recurrence after RT and RP.https://www.vestnik-grekova.ru/jour/article/view/138psakinetic performanceprostate cancerpetctradiotherapyradical prostatectomylocal recurrence |
| spellingShingle | M. A. Rybalov I. Ya. De Iong A. I. Breusma S. Kh. Al’-Shukri S. Yu. Borovets ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER Вестник хирургии имени И.И. Грекова psa kinetic performance prostate cancer pet ct radiotherapy radical prostatectomy local recurrence |
| title | ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER |
| title_full | ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER |
| title_fullStr | ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER |
| title_full_unstemmed | ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER |
| title_short | ROLE OF KINETIC PERFORMANCE OF PSA IN SELECTION OF THE PATIENTS FOR CONDUCTION OF ¹¹C-CHOLINE PET/CT AIMED TO REVEAL LOCAL RECURRENCES OF PROSTATE CANCER |
| title_sort | role of kinetic performance of psa in selection of the patients for conduction of ¹¹c choline pet ct aimed to reveal local recurrences of prostate cancer |
| topic | psa kinetic performance prostate cancer pet ct radiotherapy radical prostatectomy local recurrence |
| url | https://www.vestnik-grekova.ru/jour/article/view/138 |
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