Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets.
DNA binding transcriptional activators play a central role in gene-selective regulation. In part, this is mediated by targeting local covalent modifications of histone tails. Transcriptional regulation has also been associated with the positioning of genes within the nucleus. We have now examined th...
Main Authors: | Reini F Luco, Miguel A Maestro, Nicolas Sadoni, Daniele Zink, Jorge Ferrer |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-05-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2375116?pdf=render |
Similar Items
-
Methods in subnuclear physics/
by: Nikolic, M.
Published: (1968) -
The whys of subnuclear physics /
by: International School of Subnuclear Physics (1977 : Erice, Italy), et al.
Published: (1979) -
Intrinsic protein disorder is insufficient to drive subnuclear clustering in embryonic transcription factors
by: Colleen E Hannon, et al.
Published: (2024-01-01) -
New phenomena in subnuclear physics : proceedings /
by: International School of Subnuclear Physics (1975 : Erice, Italy), et al.
Published: (1975) -
Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.
by: Servitja, J, et al.
Published: (2009)